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Publications associées (6)

The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation

Andrea Ablasser, Baptiste Claude André Guey, Jonathan Jean-Pierre Ricci, Pauline Ambre Melenec, Ying Liu, Pengbiao Xu, Chong Liu, Lingyun Li

Cyclic GMP-AMP synthase (cGAS) senses aberrant DNA during infection, cancer and inflammatory disease, and initiates potent innate immune responses through the synthesis of 2 ' 3 '-cyclic GMP-AMP (cGAMP)1-7. The indiscriminate activity of cGAS towards DNA d ...

Nature Portfolio2024

cGAS-STING drives ageing-related inflammation and neurodegeneration

Bastien Mangeat, Natasha Ella Samson, Andrea Ablasser, Muhammet Fatih Gülen, Sélène-Véronique Glück, Vivek Vijay Thacker, Chong Liu, Alexander Scott Keller

Low-grade inflammation is a hallmark of old age and a central driver of ageing-associated impairment and disease(1). Multiple factors can contribute to ageing-associated inflammation(2); however, the molecular pathways that transduce aberrant inflammatory ...

2023

Fine-tuning the coordination atoms of copper redox mediators: an effective strategy for boosting the photovoltage of dye-sensitized solar cells

Ulf Anders Hagfeldt, Chong Liu

Natural systems have marvelously utilized copper complexes featuring sulfur-coordinating ligands, known as blue copper proteins, as efficient electron-transfer mediators in biological processes. Copper complexes with sulfur-coordinating ligands have been a ...

Royal Society of Chemistry2019

Clathrin-associated AP-1 control stermination of STING signalling

Sophie Marie Elisabeth Rivara, Andrea Ablasser, Jonathan Jean-Pierre Ricci, Ying Liu, Pengbiao Xu, Chong Liu

Stimulator of interferon genes (STING) functions downstream of cyclic GMP-AMP synthase in DNA sensing or as a direct receptor for bacterial cyclic dinucleotides and small molecules to activate immunity during infection, cancer and immunotherapy(1-10). Prec ...

NATURE PORTFOLIO2022

Fast-adaptive super-resolution lattice light-sheet microscopy for rapid, long-term, near-isotropic subcellular imaging

Chong Liu

Lattice light-sheet microscopy provides a crucial observation window into intra- and intercellular physiology of living specimens but at the diffraction-limited resolution or anisotropic super-resolution with structured illumination. Here we present meta-l ...

Nature Publishing Group2025