Publications de Gian Luca Barbruni

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Wireless, miniaturised and distributed neural interfaces are emerging neurotechnologies. Although extensive research efforts contribute to their technological advancement, the need for real-time systems enabling simultaneous wireless information and power ...

Over the last decades, implantable neural interfaces have been extensively explored and effectively deployed to address neurological and mental health disorders. The existing solutions present several limitations. Firstly, the physical size of the implanta ...

During the past two decades, a number of two-terminal switching devices have been demonstrated in the literature. They typically exhibit hysteric behavior in the current-to-voltage characteristics. These devices have often been also referred to as memristi ...

Closed-loop neural implants based on continuous brain activity recording and intracortical microstimulation are extremely effective and promising devices to monitor and address many neurodegenerative diseases. The efficiency of these devices depends on the ...

Over the past decade, significant advancements have been made in the study of silicon nanowires (SiNWs). These nanoscaled devices can exhibit a memristive type of hysteresis in the current/voltage (I/V) plane that has been utilized in the biosensors leadin ...

Label-free biosensors, combined with miniaturized micro-electromechanical sensory platforms, offer an attractive solution for real-time and facile monitoring of biomolecules due to their high sensitivity and selectivity without the need for specifically la ...

Traditional analog front-ends for biomedical signal acquisitions operate at very low frequencies (Hz-range) and are severely affected by flicker and environmental noise, which degrade the quality of low-frequency signals, thereby reducing the signal-to-noi ...

Capacitive micromachined ultrasonic transducers (CMUTs) operating at the series and parallel resonant frequencies, have shown a great potential in ultrasonic application and in biodetection. However, previous equivalent circuits rarely consider the fitting ...

The present invention concerns a bodily implantable or probe device and microelectrode fabrication method comprising providing at least one silicon substrate including an electronic device or unit; providing, on a first side of the silicon substrate, at le ...

This paper presents an ultra-miniaturized, ultra-low-power, capacitor-less CMOS ring oscillator based on dynamic leakage suppression technique. Measurement results demonstrated an oscillation frequency of 21.89 kHz and a power consumption of 7.9 nW for a s ...

Gravimetric resonant-inspired biosensors have attracted increasing attention in industrial and point-of- care applications, enabling label-free detection of biomarkers such as DNA and antibodies. Capacitive micromachined ultrasonic transducers (CMUTs) are ...

Simultaneous wireless information and power transfer is an emerging technique in neurotechnology. This work presents an efficient transmitter for both power transfer and downlink data communication to multiple, miniaturised and inductively-powered chips. W ...

In this study, we propose the development and simulation of an electrochemical aptamer biosensor designed for point-of-care detection of tuberculosis (TB) in human urine. The biosensor operates through amperometric biosensing combined with aptamer-antibody ...

Electrochemical sensors integrated with CMOS circuits play a pivotal role in quantifying various chemicals across a huge spectrum of applications, prominently in distributed diagnostics and remote monitoring. When designing integrated devices, meticulous c ...

Over the years, several clock and data recovery architectures have been proposed for wireless Amplitude Shift Keying (ASK) transmitted signals. State-of-the-art architectures mainly rely on synchronous phase-locked loop circuits or selfsampling systems, bo ...

We present here the first ever-reported direct computation of the cancer risk on cancer markers simultaneously detected by memristors. The novel approach in cancer diagnostics here proposed is based on the fusion of the three actions of sensing, computing ...

In this paper, we are presenting a new architecture to directly compute the ‘Percent-free PSA’ diagnostics index to enhance the differentiation of prostate cancer from benign prostatic disease. The proposed circuit uses silicon nanowires-based memristive b ...

Microcantilever-based biosensors have emerged as promising technologies for point-of-care sensing systems. However, since they are typically utilized as a single piezoresistor in a quarter Wheatstone bridge configuration, they suffer from output asymmetry ...

In this work, we study the effect of transistor downscaling in a wireless communication circuit for Body Dust application. The system requires a chip lateral size smaller than 10 mu m miming the typical size of a red blood cell and so, supporting free circ ...

Three-coil inductive power transfer is the state-of-the-art solution to power multiple miniaturised neural implants. However, the maximum delivered power is limited by the efficiency of the powering link and safety constrains. Here we propose a frequency-s ...

Gian Luca Barbruni

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A Wearable Real-Time System for Simultaneous Wireless Power and Data Transmission to Cortical Visual Prosthesis

Miniaturised, Wireless and Distributed Neural Interface Toward Cortical Visual Prosthesis

In-Memory Sensing and Computing for Cancer Diagnostics: A Perspective Paper

Changes Over Time in the Electrode/Brain Interface Impedance: An Ex-Vivo Study

New Insights Into the I/V Hysteretic Characteristics of Memristive Biosensors

A Front-End CMOS Interface Circuit With High Voltage Charge Pump and Oscillator for Capacitive Micromachined Ultrasonic Transducers

New Sensory Method for Neural Activity by Frequency Upconversion With Nonlinear Element

Equivalent Circuit Analysis of CMUTs-based Device for Measurement in Liquid Samples

Bodily implant microelectrode and bodily implant microelectrode fabrication method

A 69 µm2 Sub-nW/kHz Capacitor-less Ring Oscillator for Ultra-Miniaturized Implants

Development of an Integrated CMUTs-Based Resonant Biosensor for Label-Free Detection of DNA with Improved Selectivity by Ethylene- Glycol Alkanethiols

A 20 Mbps, 433 MHz RF ASK Transmitter to Inductively Power a Distributed Network of Miniaturised Neural Implants

Amperometric Urine Biosensor for Rapid Point-of-Care Tuberculosis Diagnosis

A More Reliable Equivalent Circuit of Electrochemical Sensors for Robust Design of CMOS Front-ends

An Ultra-Miniaturised CMOS Clock and Data Recovery System for Wireless ASK Transmission

A Novel Approach in Edge Computing: In-Memory Sensing of Cancer Markers

Enhancing Prostate Cancer Diagnosis with In-Memory Sensing and Edge Computing of Percent-free PSA Index

A Novel Piezoresistive Microcantilever Structure for Free Valproic Acid Sensing in Personalized Epilepsy Management

From 0.18 mu m to 28nm CMOS Down-scaling for Data Links in Body Dust Applications

A Frequency-Switching Inductive Power Transfer System for Wireless, Miniaturised and Large-Scale Neural Interfaces