Publications de Jonathan Mark Voss

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The dynamics of proteins that are associated with their function typically occur on the microsecond timescale, orders of magnitude faster than the time resolution of cryo-electron microscopy. We have recently introduced a novel approach to time-resolved cr ...

Plasmonic nanoparticles in aqueous solution have long been known to fragment under irradiation with intense ultrafast laser pulses, creating progeny particles with diameters of a few nanometers. However, the mechanism of this process is still intensely deb ...

Reshaping plasmonic nanoparticles with laser pulses has been extensively researched as a tool for tuning their properties. However, in the absence of direct observations of the processes involved, important mechanistic details have remained elusive. Here, ...

In this manuscript, we describe a simple and accurate method for finding the temporal overlap of the laser pump and electron probe pulse in ultrafast TEM. Our approach is based on the observation that the outline of a nanoparticle blurs at time zero, a phe ...

A microsecond time-resolved version of cryo-electron microscopy (cryo-EM) has recently been introduced to enable observation of the fast conformational motions of proteins. The technique involves locally melting a cryo sample with a laser beam to allow the ...

Proteins typically undergo dynamics on the microsecond to millisecond timescale, which is much faster than the time resolution of cryo-electron microscopy. Here, we propose a novel approach for microsecond time-resolved cryo-electron microscopy that involv ...

The manipulation of liquids at nanoscale dimensions is a central goal of the emergent nanofluidics field. Such endeavors extend to nanodroplets, which are ubiquitous objects involved in many technological applications. Here, we employ time-resolved electro ...

Jonathan Mark Voss

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Microsecond melting and revitrification of cryo samples

The fragmentation mechanism of gold nanoparticles in water under femtosecond laser irradiation

In Situ Observation of Coulomb Fission of Individual Plasmonic Nanoparticles

Accurate time zero determination in an ultrafast transmission electron microscope without energy filter

Near-atomic resolution reconstructions from in situ revitrified cryo samples

Rapid melting and revitrification as an approach to microsecond time-resolved cryo-electron microscopy

Real-time observation of jumping and spinning nanodroplets