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Transcranial (electro)magnetic stimulation (TMS) is currently the method of choice to non-invasively induce neural activity in the human brain. A single transcranial stimulus induces a time-varying electric field in the brain that may evoke action potentia ...

Humans have a distinguishing ability for fine motor control that is subserved by a highly evolved cortico-motor neuronal network. The acquisition of a particular motor skill involves a long series of practice movements, trial and error, adjustment and refi ...

Previous single-site neurostimulation experiments have unsuccessfully attempted to shift decision-making away from habitual control, a fast, inflexible cognitive strategy, towards goal-directed control, a flexible, though computationally expensive strategy ...

Despite recent improvements, complete motor recovery occurs in < 15% of stroke patients. To improve the therapeutic outcomes, there is a strong need to tailor treatments to each individual patient. However, there is a lack of knowledge concerning the preci ...

Aging populations face significant cognitive challenges, particularly in working memory (WM). Transcranial alternating current stimulation (tACS) offer promising avenues for cognitive enhancement, especially when inspired by brain physiology. This study (N ...

Reinforcement feedback can improve motor learning, but the underlying brain mechanisms remain underexplored. In particular, the causal contribution of specific patterns of oscillatory activity within the human striatum is unknown. To address this question, ...

Healthy aging often entails a decline in cognitive and motor functions, affecting independence and quality of life in older adults. Brain stimulation shows potential to enhance these functions, but studies show variable effects. Previous studies have tried ...

Practicing a previously unknown motor sequence often leads to the consolidation of motor chunks, which enable its accurate execution at increasing speeds. Recent imaging studies suggest the function of these structures to be more related to the encoding, s ...

Variability in the response of individuals to various non-invasive brain stimulation protocols is a major problem that limits their potential for clinical applications. Baseline motor-evoked potential (MEP) amplitude is the key predictor of an individual's ...

The cerebellum is best known for its role in controlling motor behaviors. However, recent work supports the view that it also influences non-motor behaviors. The contribution of the cerebellum towards different brain functions is underscored by its involve ...

The stimulation of deep brain structures has thus far only been possible with invasive methods. Transcranial electrical temporal interference stimulation (tTIS) is a novel, noninvasive technology that might overcome this limitation. The initial proof-of-co ...

Objective: The extent of plastic responses of motor cortex (M1) to paired associative stimulation (PAS) varies among healthy subjects. Continuous theta-burst stimulation (cTBS) of cerebellum enhances the mean PAS-induced plasticity in groups of healthy sub ...

Objective: Depotentiation of homosynaptic plasticity of the primary motor cortex (M1) is impaired in patients with Parkinson's disease (PD) who have developed dyskinesias. In this exploratory study, we tested whether this holds true for heterosynaptic plas ...

Because of the depth of the hippocampal-entorhinal complex (HC-EC) in the brain, understanding of its role in spatial navigation via neuromodulation was limited in humans. Here, we aimed to better elucidate this relationship in healthy volunteers, using tr ...

Stroke is one of the main causes of long-term disability worldwide, placing a large burden on individuals and society. Rehabilitation after stroke consists of an iterative process involving assessments and specialized training, aspects often constrained by ...

Traian Popa

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Transcranial magnetic stimulation of the brain: What is stimulated? - A consensus and critical position paper

The role of the inferior parietal lobule in writer's cramp

The effect of frontoparietal paired associative stimulation on decision-making and working memory

Toward individualized medicine in stroke-The TiMeS project: Protocol of longitudinal, multi-modal, multi-domain study in stroke

Physiology-inspired bifocal fronto-parietal tACS for working memory enhancement

Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

Native learning ability and not age determines the effects of brain stimulation

Dissecting motor skill acquisition: Spatial coordinates take precedence

Inter-Individual Variability in Motor Output Is Driven by Recruitment Gain in the Corticospinal Tract Rather Than Motor Threshold

Consensus Paper: Experimental Neurostimulation of the Cerebellum

Noninvasive theta-burst stimulation of the human striatum enhances striatal activity and motor skill learning

Plastic responsiveness of motor cortex to paired associative stimulation depends on cerebellar input

Depotentiation of associative plasticity is intact in Parkinson's disease with mild dyskinesia

Noninvasive modulation of the hippocampal-entorhinal complex during spatial navigation in humans

Replicable effect of cortical-paired associative stimulation on response inhibition as a function of age

Wearable technology in stroke rehabilitation: towards improved diagnosis and treatment of upper-limb motor impairment

Feasibility of home-based, self-applied transcranial direct current stimulation to enhance motor learning in middle-aged and older adults