Dunja Simicic

Cette personne n’est plus à l’EPFL

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Publications associées (30)

Advanced metabolite mapping at ultra-high field using 1H-MRS, 1H-MRSI and macromolecules: applications in a rat model of type C hepatic encephalopathy

Dunja Simicic

Magnetic Resonance Spectroscopy (MRS) is the only technique capable of measuring a large number of metabolites simultaneously in vivo. Ultra-high magnetic fields (UHF) combined with ultra-short echo time (TE) sequences allow the detection of high-quality 1 ...

EPFL2022

Quantitative FDG-PET and 1H-MRS reveal altered glucose uptake and neurometabolic profiles in BDL rats

Bernard Lanz, Carole Poitry-Yamate, Cristina Ramona Cudalbu, Mario Gaetano Lepore, Dunja Simicic, Ting Yin, Jessie Julie Mosso

SAGE PUBLICATIONS INC2022

PET CMRglc mapping and H-1-MRS show altered glucose uptake and neurometabolic profiles in BDL rats

Bernard Lanz, Carole Poitry-Yamate, Cristina Ramona Cudalbu, Mario Gaetano Lepore, Dunja Simicic, Ting Yin, Jessie Julie Mosso

Type C hepatic encephalopathy (HE) is a complex neuropsychiatric disorder occurring as a consequence of chronic liver disease. Alterations in energy metabolism have been suggested in type C HE, but in vivo studies on this matter remain sparse and have repo ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Late post‐natal neurometabolic development in healthy male rats using 1 H and 31 P Magnetic Resonance Spectroscopy

Rolf Gruetter, Cristina Ramona Cudalbu, Guillaume Donati, Veronika Rackayová, Dunja Simicic

Brain metabolism evolves rapidly during early post‐natal development in the rat. While changes in amino acids, energy metabolites, antioxidants or metabolites involved in phospholipid metabolism have been reported in the early stages, neurometabolic change ...

2021

A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

Maria del Carmen Sandi Perez, Cristina Ramona Cudalbu, Jocelin Grosse, Dunja Simicic

Creatine is an organic compound used as fast phosphate energy buffer to recycle ATP, important in tissues with high energy demand such as muscle or brain. Creatine is taken from the diet or endogenously synthetized by the enzymes AGAT and GAMT, and specifi ...

Nature Research2021

In vivo macromolecule signals in rat brain 1 H‐MR spectra at 9.4T: Parametrization, spline baseline estimation, and T 2 relaxation times

Bernard Lanz, Lijing Xin, Cristina Ramona Cudalbu, Veronika Rackayová, Dunja Simicic

Purpose Reliable detection and fitting of macromolecules (MM) are crucial for accurate quantification of brain short-echo time (TE) 1H-MR spectra. An experimentally acquired single MM spectrum is commonly used. Higher spectral resolution at ultra-high fiel ...

Wiley2021

Contribution of macromolecules to brain H-1 MR spectra: Experts' consensus recommendations

Rolf Gruetter, Lijing Xin, Hongxia Lei, Cristina Ramona Cudalbu, Veronika Rackayová, Dunja Simicic

Proton MR spectra of the brain, especially those measured at short and intermediate echo times, contain signals from mobile macromolecules (MM). A description of the main MM is provided in this consensus paper. These broad peaks of MM underlie the narrower ...

WILEY2020

In Vivo Longitudinal 1H MRS Study of Hippocampal, Cereberal and Striatal Metabolic Changes in the Adult Brain Using an Animal Model of Chronic Hepatic Encephalopathy

Katarzyna Pierzchala, Cristina Ramona Cudalbu, Veronika Rackayová, Dario Sessa, Stefanita-Octavian Mitrea, Dunja Simicic

LIPPINCOTT WILLIAMS & WILKINS2019

Brain Regional Susceptibility to Oxidative Stress in a Rat Model of Chronic Hepatic Encephalopathy: In-Vivo 1H MRS, Ex-Vivo ESR Spectroscopy and Histology Findings

Andrzej Sienkiewicz, Rolf Gruetter, Katarzyna Pierzchala, Cristina Ramona Cudalbu, Veronika Rackayová, Dario Sessa, Dunja Simicic

LIPPINCOTT WILLIAMS & WILKINS2019

Hippocampal and Cerebellar Astrocytes Morphological Alterations in a Rat Model of Chronic Hepatic Encephalopathy

Katarzyna Pierzchala, Cristina Ramona Cudalbu, Dunja Simicic

LIPPINCOTT WILLIAMS & WILKINS2019

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