Pierre-Benoit Bernard Ancey

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Glucose utilization increases in tumors, a metabolic process that is observed clinically by F-18-fluorodeoxyglucose positron emission tomography (F-18-FDG-PET). However, is increased glucose uptake important for tumor cells, and which transporters are impl ...

Solute carriers of the glucose transporter (GLUT) family mediate the first step for cellular glucose usage. The upregulation of GLUTs has been reported in numerous cancer types as a result of perturbation of gene expression or protein relocalization or sta ...

Neutrophils are the most abundant circulating leucocytes and are essential for innate immunity. In cancer, pro- or antitumor properties have been attributed to tumor-associated neutrophils (TAN). Here, focusing on TAN accumulation within lung tumors, we id ...

The anti-Ly6G antibody is used to deplete Ly6G(pos) neutrophils and study their role in diverse pathologies. However, depletion is never absolute, as Ly6G(low) neutrophils resistant to depletion rapidly emerge. Studying the functionality of these residual ...

Neutrophils are an essential part of the innate immune system. To study their importance, experimental studies often aim to deplete these cells, generally by injecting anti-Ly6G or anti-Gr1 antibodies. However, these approaches are only partially effective ...

Pierre-Benoit Bernard Ancey

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Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

Glucose transporters in cancer - from tumor cells to the tumor microenvironment

GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy

Anti-Ly6G binding and trafficking mediate positive neutrophil selection to unleash the anti-tumor efficacy of radiation therapy

Durable and controlled depletion of neutrophils in mice