Recherche

Afficher tous les résultats pour

Accueil

Personne

Jocelyne Bloch

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (57)

Long-term functionality of a soft electrode array for epidural spinal cord stimulation in a minipig model

Giuseppe Schiavone, Nicolas Vachicouras, Florian Dylan Fallegger, Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Fabien Bertrand Paul Wagner, Beatrice Barra, Jocelyne Bloch, Xiaoyang Kang

IEEE2018

System for selective spatiotemporal stimulation of the spinal cord

Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Marco Capogrosso, Jocelyne Bloch

The present disclosure refers to systems for electrical neurostimulation of a spinal cord of a subject in need of nervous system function support. In one example, a system comprises a signal processing device configured to receive signals from the subject ...

2017

A Computational Framework for the Design of Spinal Neuroprostheses

Silvestro Micera, Grégoire Courtine, Marco Capogrosso, Jocelyne Bloch

Severe Spinal Cord Injury (SCI) alters the communication between supra-spinal centers and the sensorimotor networks coordinating limb movements, which are usually located below the injury. Epidural electrical stimulation of lumbar segments has shown the ab ...

Springer International Publishing Ag2017

Electronic Dura Mater Meddling in the Central Nervous System

Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch

IMPORTANCE A growing number of neurologic treatments rely on neural implants capable of delivering electrical and chemical stimulation to targeted regions of the central nervous system for extended periods. OBJECTIVE To assess the potential of a novel clas ...

Amer Medical Assoc2017

A multidirectional gravity-assist algorithm that enhances locomotor control in patients with stroke or spinal cord injury

Auke Ijspeert, Grégoire Courtine, Selin Anil, Joachim von Zitzewitz, Rubia van den Brand, Marco Capogrosso, Jean-Baptiste Mignardot, Nicolas Francis Fumeaux, Jessica Lanini, Jocelyne Bloch

Gait recovery after neurological disorders requires remastering the interplay between body mechanics and gravitational forces. Despite the importance of gravity-dependent gait interactions and active participation for promoting this learning, these essenti ...

Amer Assoc Advancement Science2017

A brain-spine interface alleviating gait deficits after spinal cord injury in primates

Tomislav Milekovic, Jérôme Gandar, Silvestro Micera, Grégoire Courtine, Quentin Barraud, Simone Ellen Joze Duis, Eduardo Martin Moraud, Marco Capogrosso, David Allenson Borton, Jean-Baptiste Mignardot, Fabien Bertrand Paul Wagner, Elodie Rey, Jocelyne Bloch

Spinal cord injury disrupts the communication between the brain and the spinal circuits that orchestrate movement. To bypass the lesion, brain-computer interfaces(1-3) have directly linked cortical activity to electrical stimulation of muscles, and have th ...

Nature Publishing Group2016

Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury

Léonie Asboth, Jérôme Gandar, Stéphanie Lacour, Arthur Edouard Hirsch, Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Ivan Rusev Minev, Rubia van den Brand, Quentin Barraud, Simone Ellen Joze Duis, Eduardo Martin Moraud, Pavel Musienko, Marco Capogrosso, Natalia Pavlova, Julie Kreider, Laetitia Danielle Philippine Baud, Andrea Mortera, Jocelyne Bloch

Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in animal models and humans. However, the physiological principles underlying the effect of this intervention remain poorly understood, which has limited the ther ...

Nature Publishing Group2016

First steps towards adaptive deep brain stimulation in Parkinson’s disease

Ricardo Andres Chavarriaga Lozano, José del Rocio Millán Ruiz, Robert Leeb, Inaki Asier Iturrate Gil, Aleksander Sobolewski, Jocelyne Bloch

2016

Reliable BMI control using epidural ECoG by an hemiplegic user

Ricardo Andres Chavarriaga Lozano, José del Rocio Millán Ruiz, Robert Leeb, Aleksander Sobolewski, Jocelyne Bloch

2016

Neuroenergetic Response to Prolonged Cerebral Glucose Depletion after Severe Brain Injury and the Role of Lactate

Pierre Magistretti, Luc Pellerin, Jocelyne Bloch

Lactate may represent a supplemental fuel for the brain. We examined cerebral lactate metabolism during prolonged brain glucose depletion (GD) in acute brain injury (ABI) patients monitored with cerebral microdialysis (CMD). Sixty episodes of GD (defined a ...

Mary Ann Liebert2015

Automatic target validation based on neuroscientific literature mining for tractography

Jean-Cédric Chappelier, Sean Lewis Hill, Renaud Luc Richardet, David Slater, Xavier Vasques, Bogdan Draganski, Jocelyne Bloch

Target identification for tractography studies requires solid anatomical knowledge validated by an extensive literature review across species for each seed structure to be studied. Manual literature review to identify targets for a given seed region is ted ...

Frontiers Research Foundation2015

Defining Ecological Strategies in Neuroprosthetics

Grégoire Courtine, Jocelyne Bloch

Neurological disorders disrupt the equilibrium within the brain and spinal cord ecosystems. Ecology reuses, recycles, and reduces to help maintain the balance across ecosystems. Likewise, neuroprosthetics can help the brain help itself with ecoprosthetic d ...

Elsevier2015

Neuroprosthetic technologies to augment the impact of neurorehabilitation after spinal cord injury

Silvestro Micera, Grégoire Courtine, Joachim von Zitzewitz, Rubia van den Brand, Eduardo Martin Moraud, Marco Capogrosso, Jean-Baptiste Mignardot, Nicolas Francis Fumeaux, Fabien Bertrand Paul Wagner, Jocelyne Bloch

Spinal cord injury leads to a range of disabilities, including limitations in locomotor activity, that seriously diminish the patients’ autonomy and quality of life. Electrochemical neuromodulation therapies, robot-assisted rehabilitation and willpower-bas ...

2015

Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain

Pierre Magistretti, Reto Meuli, Jocelyne Bloch

Experimental evidence suggests that lactate is neuroprotective after acute brain injury; however, data in humans are lacking. We examined whether exogenous lactate supplementation improves cerebral energy metabolism in humans with traumatic brain injury (T ...

Springer Verlag2014

Cerebral extracellular lactate increase is predominantly nonischemic in patients with severe traumatic brain injury

Pierre Magistretti, Reto Meuli, Jocelyne Bloch

Growing evidence suggests that endogenous lactate is an important substrate for neurons. This study aimed to examine cerebral lactate metabolism and its relationship with brain perfusion in patients with severe traumatic brain injury (TBI). A prospective c ...

Nature Publishing Group2013

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status (vol 124, pg 547, 2012)

Mauro Delorenzi, Jocelyne Bloch

Springer2013

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

Mauro Delorenzi, Jocelyne Bloch

The methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) gene is an important predictive biomarker for benefit from alkylating agent therapy in glioblastoma. Recent studies in anaplastic glioma suggest a prognostic value for MGMT methyl ...

Springer-Verlag2012

Page 3 sur 3