Publications de Linlin Cao | EPFL Graph Search

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Gain-of-function mutations in NOTCH1 are among the most frequent genetic alterations in T-cell acute lymphoblastic leukemia (T-ALL), highlighting the Notch signaling pathway as a promising therapeutic target for personalized medicine. Yet, a major limitati ...

We report measurements of isospin asymmetry Delta(0-) and difference of direct CP asymmetries Delta A(CP) between charged and neutral B -> X-s gamma decays. This analysis is based on the data sample containing 772 x 10(6)B (B) over bar pairs that was colle ...

T cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy caused by acquisition of genetic alterations during T-cell development. The 5-year overall survival of pediatric T-ALL patients has improved considerably over the past 30 ...

We report evidence for the charged charmed-strange baryon Xi(c)(2930)(+) with a signal significance of 3.9 sigma with systematic errors included. The charged Xi(c)(2930)(+) is found in its decay to K-S(0)Lambda(+)(c) in the substructure of (B) over bar (0) ...

We report the results of a search for the B -> Y(4260)K, Y(4260) -> J/psi pi(+)pi thorn p-decays. This study is based on a data sample corresponding to an integrated luminosity of 711 fb(-1), collected at the Upsilon(4S) resonance with the Belle detector a ...

We have searched for the lepton-flavor-violating decay B-0 -> K-*0 mu(+/-)e(-/+) using a data sample of 711 fb(-1) that contains 772 x 10(6) B (B) over bar pairs. The data were collected near the Upsilon(4S) resonance with the Belle detector at the KEKB as ...

Inhibition of the eIF4A RNA helicase with silvestrol and related compounds is emerging as a powerful anti-cancer strategy. We find that a synthetic silvestrol analogue (CR-1-31 B) has nanomolar activity across many cancer cell lines. It is especially activ ...

We report searches for the processes e(+) e(-) -> pi(+)pi(-)pi(0)chi(bJ) and e(+) e(-) -> phi chi(bJ) ( J = 1, 2) based on data samples collected by the Belle experiment at the KEKB collider. We report the first observation of the process e(+) e(-) -> (pi( ...

We present the result of the search for the rare B meson decay of B+ -> l(+)nu e gamma with l = e, mu. For the search the full data set recorded by the Belle experiment of 711 fb(-1) integrated luminosity near the Upsilon(4S) resonance is used. Signal cand ...

Notch pathway signaling is implicated in several human cancers. Aberrant activation and mutations of Notch signaling components are linked to tumor initiation, maintenance, and resistance to cancer therapy. Several strategies, such as monoclonal antibodies ...

We measure the branching fraction and time-dependent CP-violating asymmetry for B-0 -> /psi pi(0) decays using a data sample of 711 fb(-1) collected on the Gamma(4S) resonance by the Belle experiment running at the KEKB e(+)e(-) collider. The branching fra ...

The activation of memory T cells is a very rapid and concerted cellular response that requires coordination between cellular processes in different compartments and on different time scales. In this study, we use ribosome profiling and deep RNA sequencing ...

Using data samples of 89.5 fb(-1), 711.0 fb(-1), and 121.4 fb(-1) collected with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider at center-of-mass energies 10.52, 10.58, and 10.867 GeV, respectively, we study the exclusive reactions e(+) ...

We report on the first Belle search for a light CP-odd Higgs boson, A(0), that decays into low mass dark matter, chi, in final states with a single photon and missing energy. We search for events produced via the dipion transition (sic)(2S) -> (sic)(1S)pi( ...

Linlin Cao

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Resistance mechanism to Notch inhibition and combination therapy in human T-cell acute lymphoblastic leukemia

Measurements of isospin asymmetry and difference of direct CP asymmetries in inclusive B -> X-s gamma decays

Resistance mechanism to Notch inhibition and combination therapy in human T cell acute lymphoblastic leukemia

Evidence of a structure in (K)over-bar(0)Lambda(+)(c) consistent with a charged Xi(c)(2930)(+), and updated measurement of (B)over-bar(0) -> (K)over-bar(0)Lambda(+)(c) (Lambda)over-bar(c)(-) at Belle

Search for the B -> Y(4260)K, Y(4260) -> J/psi pi(+)pi(-) decays

Search for the lepton-flavor-violating decay B-0 -> K-*0 mu(+/-)e(-/+)

NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy

Observation of e(+) e(-) -> pi(+) pi(-) pi(0)chi(b1,2) (1P) and search for e(+) e (-) -> phi chi(b1,2) (1P) at root s=10.96-11.05 GeV

Search for the rare decay of B+ -> l(+)nu e gamma with improved hadronic tagging

Pharmacological disruption of the Notch transcription factor complex

Measurement of the branching fraction and time-dependent CP asymmetry for B-0 -> J/psi pi(0) decays

A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes

Observation of e(+) e(-) -> gamma chi(c1) and search for e(+) e(-) -> gamma chi(c0), gamma chi(c2), and gamma eta(c) at root s near 10.6 GeV at Belle

Search for a Light CP-odd Higgs Boson and Low-Mass Dark Matter at the Belle Experiment