Maartje Martina Cornelia Bastings

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Publications associées (29)

DNA origami nanostructures for controlled therapeutic drug delivery

Maartje Martina Cornelia Bastings, Jorieke Weiden

DNA nanostructures are emerging as a versatile platform for controlled drug delivery as a result of recent progress in production yield and strategies to obtain prolonged stability in biological environments. The construction of nanostructures from this un ...

2021

Quantification of Strand Accessibility in Biostable DNA Origami with Single-Staple Resolution

Maartje Martina Cornelia Bastings, Alice Comberlato

DNA-based nanostructures are actively gaining interest as tools for biomedical and therapeutic applications following the recent development of protective coating strategies prolonging structural integrity in physiological conditions. For tailored biologic ...

AMER CHEMICAL SOC2021

Probing the importance of valency and spatial organization of immune regulator PD-1 with DNA-based nanomaterials

Kaltrina Paloja, Maartje Martina Cornelia Bastings, Alice Comberlato, Cem Tekin, Jorieke Weiden

WILEY2021

Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip

Maartje Martina Cornelia Bastings

Extracellular vesicles (EVs) derived from various stem cell sources induce cardioprotective effects during ischemia-reperfusion injury (IRI). These have been attributed mainly to the antiapoptotic, proangiogenic, microRNA (miRNA) cargo within the stem cell ...

AMER ASSOC ADVANCEMENT SCIENCE2020

Large‐Range HS‐AFM Imaging of DNA Self‐Assembly through In Situ Data‐Driven Control

Alireza Karimi, Georg Fantner, Adrian Pascal Nievergelt, Christoph Manuel Kammer, Maartje Martina Cornelia Bastings, Charlène Cécile Geneviève Brillard, Eva Eugene Kurisinkal

Understanding hierarchical self-assembly of biological structures requires real time measurement of the self-assembly process over a broad range of length- and timescales. The success of high-speed atomic force microscopy (HS-AFM) in imaging small scale mo ...

2019

Nucleic acids presenting polymer nanomaterials as vaccine adjuvants

Kaltrina Paloja, Maartje Martina Cornelia Bastings, Alice Comberlato

Most vaccines developed today include only the antigens that best stimulate the immune system rather than the entire virus or microbe, which makes vaccine production and use safer and easier, though they lack potency to induce acceptable immunity and long- ...

Royal Society of Chemistry2019

Engineering a stable future for DNA-origami as a biomaterial

Hale Bila, Maartje Martina Cornelia Bastings, Eva Eugene Kurisinkal

DNA as a biomaterial has evoked great interest as a potential platform for therapeutics and diagnostics and as hydrogel scaffolds due to the relative ease of programming its robust and uniform shape, site-specific functionality and controlled responsive be ...

ROYAL SOC CHEMISTRY2019

Quantifying Guest-Host Dynamics in Supramolecular Assemblies to Analyze Their Robustness

Maartje Martina Cornelia Bastings, Eva Eugene Kurisinkal

The most basic function of synthetic microenvironments for tissue engineering is to act as a physical substrate for cell attachment, migration, and proliferation, similar to the natural cell environment. Functionalization of supramolecular materials with g ...

WILEY-V C H VERLAG GMBH2019

Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape

Maartje Martina Cornelia Bastings

American Chemical Society (ACS)2018

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