Publications de Tugba Kilic | EPFL Graph Search

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Schizophrenia treatment may see a paradigm shift due to development of new atypical antipsychotic drugs (APDs), with better tolerability due to more selective dopamine (DA) receptor blockade. Monitoring of these APD candidates in biological fluids is of gr ...

In this paper, we present the design, the implementation and the validation of a novel Internet of Things (IoT) drug monitoring system for the online continuous and simultaneous detection of two main anesthetics, e.g., propofol and paracetamol, in undilute ...

As being the most extensively studied, non-coding, evolutionary conserved, post-transcriptional gene regulators of genome, microRNAs (miRNAs) have taken great attention among various disciplines due to their important roles in biological processes and link ...

Nanoscale extracellular vesicles (EVs) including exosomes (50–150 nm membrane particles) have emerged as promising cancer biomarkers due to the carried genetic information about the parental cells. However the sensitive detection of these vesicles remains ...

In the proposed study, for the first time, sensitive electrochemical detection of a breast cancer biomarker microRNA (miRNA), mir-21 was achieved via electropolymerized polypyrrole (PPy) modified pencil graphite electrodes (PPy/PGE). The detection of hybri ...

The Hemolytic Disease of the Fetus and Newborn (HDFN), if untreated, can have severe consequences on baby’s health, eventually causing death. Prevention and diagnosis of pregnancies at risk of HDFN consists in quantitative analysis in hospital every 2-4 we ...

We present in this work, first time in literature, a voltammetric label-free biosensor for detection of alpha lactalbumin (alpha-LB) in meal samples. Food allergy concern necessitates strict regulations in food labelling and innovative monitoring strategie ...

The pharmaceutical industry is facing enormous challenges due to high drug attribution rates. For the past decades, novel methods have been developed for safety and efficacy testing, as well as for improving early development stages. In vitro screening met ...

In this work, we report the demonstration of the capability of electrochemical sensors to provide measurements directly on the sweat of volunteers to successfully discriminate heavy smokers by light ones. Since its importance as pharmaceutical treatment-ag ...

The ability to detect protein biomarkers at a subnanomolar level represents a pervasive challenge in order to bring a significant improvement in early diagnosis or progression of pato-physiological processes. To this aim, Screen Printed Electrochemical Sen ...

This work presents the design and the realization of a flexible front-end circuitry for electrochemical sensing with wearable devices. The hardware combines readout circuitry for amperometric and Open Circuit Potential (OCP) measurements. The sensing platf ...

In this work, we present a novel electrochemical cleaning procedure for long-term electrochemical monitoring of propofol by using boron-doped diamond (BDD) and pencil graphite electrode (PGE). Propofol is an anesthetic that is widely used for long-lasting ...

Induction of anesthesia with propofol is a largely adopted technique in hospital environments. The correct dosage of this compound is essential to avoid under- or over-anesthesia that may result in serious side-effects. Therefore, in clinical settings, lon ...

Complementary Metal-Oxide Semiconductor (CMOS)-based microanalysis involves a wide variety of devices, technologies, methods, and approaches, as extensively detailed in scientific literature. For example, we can find the use of CMOS- in investigations on p ...

A Pencil Graphite Electrode (PGE) is herein disclosed. The electrode is characterized by a reduced content in graphite and an increased content in clay of the composite material composing it compared to the prior art PGEs. In particular, the PGE according ...

As a paradigm shifting player of tissue engineering, organs-on-chips (OOCs) are considered to hold great potential for future “clinical trials on chip” as well as a step forward to design personalized medicine. Despite all ethical concerns raised by commun ...

Tugba Kilic

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A novel psychoanalytical approach: An electrochemical ligand-binding assay to screen antipsychotics

An IoT Solution for Online Monitoring of Anesthetics in Human Serum Based on an Integrated Fluidic Bioelectronic System

microRNA biosensors: Opportunities and challenges among conventional and commercially available techniques

Label-free detection of hypoxia-induced extracellular vesicle secretion from MCF-7 cells

A novel method for sensitive microRNA detection: Electropolymerization based doping

An electrochemical sensor for quantitative analysis of Rhesus D antibodies in blood

Milk Allergen Detection: Sensitive Label-Free Voltammetric Immunosensor Based on Electropolymerization

Mining the Potential of Label-Free Biosensors for In Vitro Antipsychotic Drug Screening

Electrochemical determination of nicotine in smokers' sweat

Enhanced Sensing of Interleukin 8 by Stripping Voltammetry: Carbon Nanotubes versus Fullerene

A Flexible Front-End for Wearable Electrochemical Sensing

Cleaning strategy for carbon-based electrodes: Long-term propofol monitoring in human serum

Raspberry-Pi based system for propofol monitoring

CMOS-based microanalysis systems

Fouling-resistant pencil graphite electrode

Organs-on-chip monitoring: sensors and other strategies