Publications de Lucille Delisle

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Galaxy is a mature, browser accessible workbench for scientific computing. It enables scientists to share, analyze and visualize their own data, with minimal technical impediments. A thriving global community continues to use, maintain and contribute to th ...

Understanding the interplay between cell fate specification and morphogenetic changes remains a challenge in developmental biology. Gastruloids, stem cell models of postimplantation mammalian development, provide a platform to address this question. Here, ...

Mammalian tail length is controlled by several genetic determinants, among which are Hox13 genes, whose function is to terminate the body axis. Accordingly, the precise timing in the transcriptional activation of these genes may impact upon body length. Un ...

Self-organization, such as the emergence of a pattern from a homogenous state, is a fascinating property of biological systems. Early limb bud outgrowth and patterning in mice are controlled by a robust and self-regulatory signaling system, and initiation ...

Chondrocyte differentiation controls skeleton development and stature. Here we provide a comprehensive map of chondrocyte-specific enhancers and show that they provide a mechanistic framework through which non-coding genetic variants can influence skeletal ...

Motivation Generating publication ready plots to display multiple genomic tracks can pose a serious challenge. Making desirable and accurate figures requires considerable effort. This is usually done by hand or using a vector graphic software. ...

Lucille Delisle

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The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update

Size-dependent temporal decoupling of morphogenesis and transcriptional programs in pseudoembryos

CTCF-dependent insulation of Hoxb13 and the heterochronic control of tail length

WNT signaling coordinately controls mouse limb bud outgrowth and establishment of the digit-interdigit pattern

Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton development

pyGenomeTracks: reproducible plots for multivariate genomic datasets