Publications de Jan Dedic | EPFL Graph Search

Publications associées (7)

Soft matter probed by nonlinear scattering: self-assembly, interfaces, hydration, and long-range order

All organisms are made to a large extent of soft matter - macromolecules such as proteins and polysaccharides, or assemblies of small molecules such as lipids embedded in an aqueous environment. Understanding the role of order in soft matter presents a cha ...

EPFL2020

Hyaluronan orders water molecules in its nanoscale extended hydration shells

Sylvie Roke, Halil Ibrahim Okur, Jan Dedic

Hyaluronan (HA) is an anionic, highly hydrated bio-polyelectrolyte found in the extracellular environment, like the synovial fluid between joints. We explore the extended hydration shell structure of HA in water using femto-second elastic second-harmonic s ...

AMER ASSOC ADVANCEMENT SCIENCE2021

Lysozyme Interaction with Phospholipid Nanodroplets Probed by Sum Frequency Scattering Vibrational Spectroscopy

Sylvie Roke, Halil Ibrahim Okur, Jan Dedic, Sergey Kulik

When a nanoparticle (NP) is introduced into a biological environment, its identity and interactions are immediately attributed to the dense layer of proteins that quickly covers the particle. The formation of this layer, dubbed the protein corona, is in ge ...

AMER CHEMICAL SOC2023

Membrane–Protein–Hydration Interaction of α-Synuclein with Anionic Vesicles Probed via Angle-Resolved Second-Harmonic Scattering

Sylvie Roke, Jan Dedic, Halil Ibrahim Okur

Amyloid formation of the protein α-synuclein promotes neurodegeneration in Parkinson's disease. The normal function of α-synuclein includes synaptic vesicle transport and fusion, and the protein binds strongly to negatively charged vesicles in vitro. Here, ...

2019

Comment on "Water- water correlations in electrolyte solutions probed by hyper-Rayleigh scattering" [J. Chem. Phys. 147, 214505 (2017)]

Yixing Chen, Michele Ceriotti, Sylvie Roke, Halil Ibrahim Okur, David Mark Wilkins, Nathan Dupertuis, Jan Dedic

AMER INST PHYSICS2018

Polyelectrolytes induce water-water correlations that result in dramatic viscosity changes and nuclear quantum effects

Sylvie Roke, Halil Ibrahim Okur, Jan Dedic

Ions interact with water via short-ranged ion-dipole interactions. Recently, an additional unexpected long-ranged interaction was found: The total electric field of ions influences water-water correlations over tens of hydration shells, leading to the Jone ...

American Association for the Advancement of Science (AAAS)2019

Membrane-protein-hydration interaction of alpha-synuclein with anionic vesicles in solution probed via angle-resolved second harmonic scattering

Sylvie Roke, Jan Dedic

AMER CHEMICAL SOC2019