Charlotte Avanzi

Cette personne n’est plus à l’EPFL

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Publications associées (24)

Transmission of drug-resistant leprosy in Guinea-Conakry detected by molecular epidemiological approaches

Stewart Cole, Philippe Busso, Chloé Marie Loiseau, Andrej Benjak, Charlotte Avanzi

Molecular drug susceptibility testing was performed on skin biopsies from 24 leprosy patients from Guinea-Conakry for the first time. We identified primary drug resistance in 4 cases and a dapsone-resistant cluster caused by the same strain. Primary transm ...

Oxford Univ Press Inc2016

Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis

Stewart Cole, Philippe Busso, Pushpendra Singh, Andrej Benjak, Charlotte Avanzi

Mycobacterium lepromatosis is an uncultured human pathogen associated with diffuse lepromatous leprosy and a reactional state known as Lucio's phenomenon. By using deep sequencing with and without DNA enrichment, we obtained the near-complete genome sequen ...

National Academy of Sciences2015

Mycobacterium lepromatosis Infections in Nuevo Leon, Mexico

Stewart Cole, Philippe Busso, Pushpendra Singh, Andrej Benjak, Charlotte Avanzi

The frequency of infection caused by the recently described pathogen Mycobacterium lepromatosis is unknown. Here, we describe the demographics, clinical characteristics, and therapeutic outcomes of five lepromatous leprosy patients suffering from M. leprom ...

American Society for Microbiology2015

Genome-wide re-sequencing of multidrug-resistant Mycobacterium leprae Airaku-3

Stewart Cole, Jacques Rougemont, Philippe Busso, Pushpendra Singh, Andrej Benjak, Charlotte Avanzi

Genotyping and molecular characterization of drug resistance mechanisms in Mycobacterium leprae enables disease transmission and drug resistance trends to be monitored. In the present study, we performed genome-wide analysis of Airaku-3, a multidrug-resist ...

Wiley-Blackwell2014

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