Emulsions of two immiscible liquids can slowly coalesce over time when stabilized by surfactant molecules. Pickering emulsions stabilized by colloidal particles can be much more stable. Here, we fabricate biocompatible amphiphilic dimer particles using a h ...
This reply to the comment by Nakajima on our article that appeared in Lab on a Chip (E. Amstad, M. Chemama, M. Eggersdorfer, L. R. Arriaga, M. Brenner and D. A. Weitz, Lab Chip, 2016, 16, 4163-4172) highlights the differences between the microchannel step ...
Particles and capsules are used as containers for active ingredients to delay their degradation and control the location and kinetics of their release. Key to a successful application of these containers is a good control over their size, composition, and ...
Compressed monodisperse emulsions in confined space exhibit highly ordered structures. The influence of the volume fraction and the confinement geometry on the organized structures is investigated and the mechanism by which structural transition occurs is ...
Microfluidic flow-focusing devices offer excellent control over fluid flow, enabling formation of drops with a narrow size distribution. However, the throughput of microfluidic flow-focusing devices is limited and scale-up through operation of multiple dro ...
Capsules are often used as mobile delivery vehicles, for example, in pharmacy, food, and cosmetics, or as stationary containers that are embedded in a matrix to functionalize materials. Progress achieved in polymer chemistry opened up new possibilities to ...
High-volume production of monodisperse droplets is of importance for industrial applications due to increased emulsion stability, precise control over droplet volumes, and the formation of periodic arranged structures. So far, parallelized microfluidic dev ...
Many powders employed in the food and pharmaceutical industries are produced through spray drying because it is a cost efficient process that offers control over the particle size. However, most commercially available spray-driers cannot produce drops with ...
Many newly developed active pharmaceutical ingredients (APIs) are poorly soluble in water and thus have a dissolution-limited bioavailability. The bioavailability of Biopharmaceutical Classification System (BCS) class II APIs increases if they dissolve fas ...
A device and method for the mechanical (partial or total) removal of the liquid phase of the external shell of a core-shell capsule is disclosed. The device comprises a main channel having at least one inlet, one outlet and a tubular element in between, ad ...
Monodisperse drops with diameters between 20 mu m and 200 mu m can be used to produce particles or capsules for many applications such as for cosmetics, food, and biotechnology. Drops composed of low viscosity fluids can be conveniently made using microflu ...
Aqueous drops of a well-defined size are often used as small containers for conducting chemical and biochemical reactions, cell assays and as templates to produce microparticles. To prevent their coalescence, they must be stabilized, for example, using sur ...
Nearly all tubes and pores used to transport solids in fluids, such as arteries and filters, are subject to clogging. The length scales and geometries of these tubes are well defined. In spite of this knowledge, the collective clogging behavior of multiple ...
Double emulsion drops are well-suited templates to produce capsules whose dimensions can be conveniently tuned by adjusting those of the drops. To closely control the release kinetics of encapsulants, the composition and thickness of the capsule shell must ...
The bioavailability of hydrophobic drugs strongly increases if they are formulated as amorphous materials because the solubility of the amorphous phase is much higher than that of the crystal. Moreover, the stability of these particles against crystallizat ...
Amorphous nanoparticles (a-NPs) have physicochemical properties distinctly different from those of the corresponding bulk crystals; for example, their solubility is much higher. However, many materials have a high propensity to crystallize and are difficul ...
American Association for the Advancement of Science2015
Formulation of hydrophobic drugs as amorphous materials is highly advantageous as this increases their solubility in water and therefore their bioavailability. However, many drugs have a high propensity to crystallize during production and storage, limitin ...
Devices and methods for dividing droplets are generally described. In some embodiments, an article may comprise a fluidic channel comprising an array of obstructions. In certain embodiments, the arrangement of obstructions in the array may affect the flow ...
A dispersant for stabilizing nanoparticles, in particular inorganic non-metallic nanoparticles is described. Said dispersant comprises at least one anchor group A, and at least one spacing group R covalently linked to said anchor group, said anchor grou ...
