Raphaël Etienne Jean Trouillon

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Magnetic micro-and nanoparticles ('magnetic beads') have been used to advantage in many microfluidic devices for sensitive antigen (Ag) detection. Today, assays that use as read-out of the signal the number count of immobilized beads on a surface for quant ...

The diffusion layer is a critical factor affecting the temporal response of electrochemical devices. In this article, we have investigated the effect of the relaxation of the diffusion layer during the potentiodynamic sensing of ferrocenemethanol (FcMeOH) ...

The time response of an electrode incorporated into a fluidic channel to variations in analyte concentration of the outer-sphere redox probe ferrocenemethanol was investigated both for amperometry (AMP) and cyclic voltammetry (CV). The experimental data sh ...

Dielectric microspheres with appropriate refractive index can image objects with super-resolution, that is, with a precision well beyond the classical diffraction limit. A microsphere is also known to generate upon illumination a photonic nanojet, which is ...

Chromogenic in situ hybridization (CISH) is a common technique that is used for human epidermal growth factor receptor 2 (HER2) assessment in breast cancer diagnosis. CISH is based on the enzymatic amplification of DNA markers, generating a colorimetric im ...

A straightforward and general way for monitoring chemical reactions is via their thermal signature. Such approach requires however an experimental setup with a high thermal stability that simultaneously allows time-resolved heat detection with high sensiti ...

We demonstrate a method to determine the Brownian motion and the diffusion coefficient of a nanoparticle in water in a plane that is parallel to a solid boundary and as function of the distance normal to that boundary by using an optical tweezers instrumen ...

The nematode Caenorhabditis elegans has been extensively used as a model multicellular organism to study the influence of osmotic stress conditions and the toxicity of chemical compounds on developmental and motility-associated phenotypes. However, the sev ...

We describe the concept of magnetic particle-scanning for on-chip detection of biomolecules: a magnetic particle, carrying a low number of antigens (Ag's) (down to a single molecule), is transported by hydrodynamic forces and is subjected to successive sto ...

The fluorescence in situ hybridization (FISH) is the gold standard in human epidermal growth factor receptor 2 (HER2) status assessment in breast cancer. The dissemination of the technique is impeded by the cost of reagents and long experimental time. For ...

Glucose uptake in muscle cells in response to insulin is a fundamental mechanism for metabolism. The inability of cells to mobilize the specific glucose transporter GLUT4 is believed to be at least partially accountable for diseases, like diabetes, where c ...

Fluorescence in situ hybridization (FISH) is one of the recommended techniques for human epidermal growth factor receptor 2 (HER2) status assessment on cancer tissues. Here we develop microfluidics-assisted FISH (MA-FISH), in which hybridization of the FIS ...

A hybrid microfluidic/electrochemical system is described for the time-resolved detection of dopamine (DA) from neuron-like PC12 cells cultured on a patch of filter paper. Cell adherence to the surface of the paper is investigated using fluorescence micros ...

We introduce a new modeling approach for understanding the fundamental principle of bead-based surface coverage immunoassays that rely on the specific interaction between surface-bound “small” magnetic beads (1 μm in diameter) and a flow of “large” magneti ...

The resistance of cathodically and anodically treated boron-doped diamond electrodes to dopamine fouling was investigated. It was found, using cyclic voltammetry and electrochemical impedance spectroscopy, that the cathodic preparation offers an increased ...

Raphaël Etienne Jean Trouillon

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Dose-response curve of a microfluidic magnetic bead-based surface coverage sandwich assay

Interplay between the potential waveform and diffusion layer dynamics determines the time-response of voltammetric detection in microchannels

Delayed voltammetric with respect to amperometric electrochemical detection of concentration changes in microchannels

Super-Resolution Imaging of a Dielectric Microsphere Is Governed by the Waist of Its Photonic Nanojet

Microfluidic-assisted chromogenic in situ hybridization (MA-CISH) for fast and accurate breast cancer diagnosis

Nanocalorimetric platform for accurate thermochemical studies in microliter volumes

Study of constrained Brownian motion of nanoparticles near an interface using optical tweezers

Automated phenotyping of Caenorhabditis elegans embryos with a high-throughput-screening microfluidic platform

Magnetic Particle-Scanning for Ultrasensitive Immunodetection On-Chip

FLUORESCENCE IN SITU HYBRIDIZATION (FISH) ENHANCEMENT USING MICROFLUIDIC FLOW FOR AN ACCURATE, FAST AND ECONOMICAL ASSESSMENT OF HER2 STATUS IN BREAST CANCER

A multiscale study of the role of dynamin in the regulation of glucose uptake

Microfluidics-assisted fluorescence in situ hybridization for advantageous human epidermal growth factor receptor 2 assessment in breast cancer

Dynamic electrochemical quantitation of dopamine release from a cells-on-paper system

A random-walk based model to explain ultrasensitive magnetic bead-based immunoassays

Cathodic pretreatment improves the resistance of boron-doped diamond electrodes to dopamine fouling

Voltammetric electrochemical detection of concentration changes in a microfluidic chip is delayed in comparison to amperometry