Quentin Barraud

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (27)

Page 2 sur 2

Preclinical upper limb neurorobotic platform to assess, rehabilitate, and develop therapies

Silvestro Micera, Stéphanie Lacour, Grégoire Courtine, Quentin Barraud, Newton Cho, Nicholas David James, Florent-Valéry Coen, Selin Anil, Inssia Dewany

Numerous neurorehabilitative, neuroprosthetic, and repair interventions aim to address the consequences of upper limb impairments after neurological disorders. Although these therapies target widely different mechanisms, they share the common need for a pr ...

AMER ASSOC ADVANCEMENT SCIENCE2022

Confronting false discoveries in single-cell differential expression

Grégoire Courtine, Gioele La Manno, Quentin Barraud, Jordan Squair, Matthieu Pierre Gautier, Mark Andrew Anderson, Nicholas David James, Thomas Haynes Hutson, Claudia Kathe, Michael Alexander Skinnider, Rémi Bernard René Hudelle

Differential expression analysis of single-cell transcriptomics allows scientists to dissect cell-type-specific responses to biological perturbations. Here, the authors show that many commonly used methods are biased and can produce false discoveries. ...

Nature Portfolio2021

Single-cell and spatial atlases of spinal cord injury in the Tabulae Paralytica

Grégoire Courtine, Bernard Schneider, Jocelyne Bloch, Quentin Barraud, Claudia Kathe, Matthieu Pierre Gautier, Nicholas David James, Thomas Haynes Hutson, Michael Alexander Skinnider, Achilleas Laskaratos, Michael V. Sofroniew, Nicola Aldo Regazzi

Here, we introduce the Tabulae Paralytica—a compilation of four atlases of spinal cord injury (SCI) comprising a single-nucleus transcriptome atlas of half a million cells, a multiome atlas pairing transcriptomic and epigenomic measurements within the same ...

Springer Science and Business Media LLC2024

Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury

Silvestro Micera, Grégoire Courtine, Pavel Musienko, Eduardo Martin Moraud, Quentin Barraud, Lucia Florinda Friedli Wittler, Kay Alexander Bartholdi

Half of human spinal cord injuries lead to chronic paralysis. Here, we introduce an electrochemical neuroprosthesis and a robotic postural interface designed to encourage supraspinally-mediated movements in rats with paralyzing lesions. Despite the interru ...

American Association for the Advancement of Science2012

Natural and targeted circuit reorganization after spinal cord injury

Grégoire Courtine, Jocelyne Bloch, Quentin Barraud, Jordan Squair, Claudia Kathe, Matthieu Pierre Gautier, Mark Andrew Anderson, Thomas Haynes Hutson

The authors summarize changes in circuits after spinal cord injury and current strategies to target these circuits in order to improve recovery, but also advocate for new concepts of reorganizing circuits informed by multi-omic single-cell atlases. ...

NATURE PORTFOLIO2022

Pharmacological stimulation to facilitate and restore standing and walking functions in spinal cord motor disorders

Grégoire Courtine, Quentin Barraud, Pavel Musienko

The invention relates to the selective targeting of specific α2 adrenergic receptor subtypes for facilitating and also restoring standing and walking in a subject affected by spinal cord disorders, in particular spinal cord injury. In particular, the impro ...

2016

Applying Whole Organ Clearing Techniques To Spinal Cord Injury: A Survey Of Techniques

Grégoire Courtine, Olivier Burri, Quentin Barraud, Romain Guiet, Thierry Laroche, Newton Cho, Laura Battista

MARY ANN LIEBERT2018