Stéphane Laurent Escrig

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Successful application of diffusion chronometry is based on detailed knowledge of diffusion parameters obtained from laboratory experiments, which also need to be upscaled to be applied to natural samples. While generally applicable, several examples of di ...

Sponges are the oldest known extant animal-microbe symbiosis. These ubiquitous benthic animals play an important role in marine ecosystems in the cycling of dissolved organic matter (DOM), the largest source of organic matter on Earth. The conventional vie ...

Recrystallization of minerals due to fluid infiltration modifies their original chemical and isotopic signature. Such processes are sought after as they give access to timescales of geologic processes, which are commonly quantified using diffusion chronome ...

High input of organic carbon and/or slowly renewing bottom waters frequently create periods with low dissolved oxygen concentrations on continental shelves and in coastal areas; such events can have strong impacts on benthic ecosystems. Among the meiofauna ...

Glucose utilization increases in tumors, a metabolic process that is observed clinically by F-18-fluorodeoxyglucose positron emission tomography (F-18-FDG-PET). However, is increased glucose uptake important for tumor cells, and which transporters are impl ...

Increasing soil salinity causes significant crop losses globally; therefore, understanding plant responses to salt (sodium) stress is of high importance. Plants avoid sodium toxicity through subcellular compartmentation by intricate processes involving a h ...

Corals access inorganic seawater nutrients through their autotrophic endosymbiotic dinoflagellates, but also capture planktonic prey through heterotrophic feeding. Correlating NanoSIMS and TEM imaging, we visualized and quantified the subcellular fate of a ...

Coral reefs are currently experiencing substantial ecological impoverishment as a result of anthropogenic stressors, and the majority of reefs are facing immediate risk. Increasing ocean surface temperatures induce frequent coral mass bleaching events—the ...

Oxygen isotope compositions of fossil foraminifera tests are commonly used proxies for ocean paleotemperatures, with reconstructions spanning the last 112 million years. However, the isotopic composition of these calcitic tests can be substantially altered ...

Crystallization timescales in subvolcanic systems and the consequences of interaction between ascending magmas and gases remain largely unconstrained, as do links between these processes and monitoring signals at restless volcanoes. We apply diffusion chro ...

beta-Amyloid (A beta) plaque formation is the major pathological hallmark of Alzheimer's disease (AD) and constitutes a potentially critical, early inducer driving AD pathogenesis as it precedes other pathological events and cognitive symptoms by decades. ...

BackgroundThe development of nanoscale secondary ion mass spectrometry (NanoSIMS) has revolutionized the study of biological tissues by enabling, e.g., the visualization and quantification of metabolic processes at subcellular length scales. However, the a ...

Changes in seawater chemistry have affected the evolution of calcifying marine organisms, including their skeletal polymorph (calcite versus aragonite), which is believed to have been strongly influenced by the Mg/Ca ratio at the time these animals first e ...

Efficient nutrient recycling underpins the ecological success of cnidarian-algal symbioses in oligotrophic waters. In these symbioses, nitrogen limitation restricts the growth of algal endosymbionts in hospite and stimulates their release of photosynthates ...

The density of dinoflagellate microalgae in the tissue of symbiotic corals is an important determinant for health and productivity of the coral animal. Yet, the specific mechanism for their regulation and the consequence for coral nutrition are insufficien ...

Some sacoglossan sea slugs incorporate intracellular functional algal chloroplasts, a process termed kleptoplasty. "Stolen" chloroplasts (kleptoplasts) can remain photosynthetically active up to several months, contributing to animal nutrition. Whether thi ...

Secondary Ion Mass Spectrometry (SIMS) extracts chemical, elemental, or isotopic information about a localized area of a solid target by performing mass spectrometry on secondary ions sputtered from its surface by the impact of a beam of charged particles. ...

The processes that lead to the fourfold variation in arc-averaged compositions of mafic arc iavas remain controversial. Control by the mantle-wedge thermal structure is supported by chemical correlations with the thickness of the underlying arc crust(1-3), ...

In Parkinson's disease, pathogenic factors such as the intraneuronal accumulation of the protein alpha-synuclein affect key metabolic processes. New approaches are required to understand how metabolic dysregulations cause degeneration of vulnerable subtype ...

Kleiber's law describes the scaling of metabolic rate with body size across several orders of magnitude in size and across taxa and is widely regarded as a fundamental law in biology. The physiological origins of Kleiber's law are still debated and general ...

Stéphane Laurent Escrig

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Diffusion timescale conundrum in contact metamorphism: Oxygen isotope and trace element profiles in dolomite

Heterotrophy in the earliest gut: a single-cell view of heterotrophic carbon and nitrogen assimilation in sponge-microbe symbioses

Dissolution-reprecipitation reaction of dolomite: investigation of self- and tracer-diffusion using SIMS mini-spot and NanoSIMS profiles

Surviving anoxia in marine sediments: The metabolic response of ubiquitous benthic foraminifera (Ammonia tepida)

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation

Temperature and feeding induce tissue level changes in autotrophic and heterotrophic nutrient allocation in the coral symbiosis – A NanoSIMS study

Common reef-building coral in the Northern Red Sea resistant to elevated temperature and acidification

Fast and pervasive diagenetic isotope exchange in foraminifera tests is species-dependent

Taking the pulse of volcanic eruptions using plagioclase glomerocrysts

Following spatial A beta aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics

Correlated cryo-SEM and CryoNanoSIMS imaging of biological tissue

Aragonitic scleractinian corals in the Cretaceous calcitic sea

Coupled carbon and nitrogen cycling regulates the cnidarian–algal symbiosis

Intracellular competition for nitrogen controls dinoflagellate population density in corals

Functional kleptoplasts intermediate incorporation of carbon and nitrogen in cells of the Sacoglossa sea slug Elysia viridis

Surface Analysis by Secondary Ion Mass Spectrometry (SIMS): Principles and Applications from Swiss Laboratories

Parental arc magma compositions dominantly controlled by mantle-wedge thermal structure

Stable isotope labeling and ultra-high-resolution NanoSIMS imaging reveal alpha-synuclein-induced changes in neuronal metabolism in vivo

Generalized size scaling of metabolic rates based on single-cell measurements with freshwater phytoplankton