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Silvestro Micera

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Publications associées (314)

Quantitative Kinematic Characterization of Reaching Impairments in Mice After a Stroke

Silvestro Micera, Stefano Lai

Background and Objective. Kinematic analysis of reaching movements is increasingly used to evaluate upper extremity function after cerebrovascular insults in humans and has also been applied to rodent models. Such analyses can require time-consuming frame- ...

Sage Publications Inc2015

EMG-Based Analysis of the Upper Limb Motion

Aude Billard, Sahar El Khoury, Silvestro Micera, Iason Batzianoulis

In a human robot interaction scenario, predicting the human motion intention is essential for avoiding inconvenient delays and for a smooth reactivity of the robotic system. In particular, when dealing with hand prosthetic devices, an early estimation of t ...

ACM2015

MOVING ALONG In biomechanics, rehabilitation engineering, and movement analysis, Italian researchers are making great strides

Silvestro Micera

In Italy, biomechanics research and the analysis of human and animal movement have had a very long history, beginning with the exceptional pioneering work of Leonardo da Vinci. In 1489, da Vinci began investigating human anatomy, including an examination o ...

Ieee-Inst Electrical Electronics Engineers Inc2015

Closed-loop neuromodulation of spinal sensorimotor circuits controls refined locomotion after complete spinal cord injury

Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Stanisa Raspopovic, Marco Bonizzato, Eduardo Martin Moraud, Pavel Musienko

Neuromodulation of spinal sensorimotor circuits improves motor control in animal models and humans with spinal cord injury. With common neuromodulation devices, electrical stimulation parameters are tuned manually and remain constant during movement. We de ...

American Association for the Advancement of Science2014

Restoring Natural Sensory Feedback in Real-Time Bidirectional Hand Prostheses

Silvestro Micera, Stanisa Raspopovic, Marco Bonizzato, Marco Capogrosso, Francesco Maria Petrini, Jacopo Rigosa

Hand loss is a highly disabling event that markedly affects the quality of life. To achieve a close to natural replacement for the lost hand, the user should be provided with the rich sensations that we naturally perceive when grasping or manipulating an o ...

American Association for the Advancement of Science2014

The effect of arm weight support on upper limb muscle synergies during reaching movements

Silvestro Micera, Martina Coscia

Background: Compensating for the effect of gravity by providing arm-weight support (WS) is a technique often utilized in the rehabilitation of patients with neurological conditions such as stroke to facilitate the performance of arm movements during therap ...

BioMed Central2014

Corticospinal neuroprostheses to restore locomotion after spinal cord injury

José del Rocio Millán Ruiz, Stéphanie Lacour, Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Ivan Rusev Minev, Marco Bonizzato, Janine Beauparlant, Eduardo Martin Moraud, Pavel Musienko, David Allenson Borton

In this conceptual review, we highlight our strategy for, and progress in the development of corticospinal neuroprostheses for restoring locomotor functions and promoting neural repair after thoracic spinal cord injury in experimental animal models. We spe ...

Elsevier2014

Pre-Impact Fall Detection: Optimal Sensor Positioning Based on a Machine Learning Paradigm

Silvestro Micera, Fiorenzo Artoni

The aim of this study was to identify the best subset of body segments that provides for a rapid and reliable detection of the transition from steady walking to a slipping event. Fifteen healthy young subjects managed unexpected perturbations during walkin ...

Public Library Science2014

A real-time research platform to study vestibular implants with gyroscopic inputs in vestibular deficient subjects

Maurizio Ranieri, Silvestro Micera, Thuy Anh Khoa Nguyen

Researchers have succeeded in partly restoring damaged vestibular functionality in several animal models. Recently, acute interventions have also been demonstrated in human patients. Our previous work on a vestibular implant for humans used predefined stim ...

2014

The effects on biomechanics of walking and balance recovery in a novel pelvis exoskeleton during zero-torque control

Silvestro Micera

Fall-related accidents are among the most serious concerns in elderly people, amputees and subjects with neurological disorders. The aim of this paper was to investigate the behaviour of healthy subjects wearing a novel light-weight pelvis exoskeleton cont ...

Cambridge University Press2014

Modular organization of reaching and grasping movements investigated using EEG microstates

Dimitri Nestor Alice Van De Ville, Robert Leeb, Elvira Pirondini, Silvestro Micera, Martina Coscia, Jesús Minguillón Campos

How movements are generated and controlled by the central nervous system (CNS) is still not well understood. In this work, we tested the hypothesis of a modular organization of the brain activity during the execution of voluntary movements. In particular, ...

IEEE2014

A Robotic System for Quantitative Assessment and Poststroke Training of Forelimb Retraction in Mice

Marco Mainardi, Silvestro Micera, Stefano Lai

Background. Neurorehabilitation protocols based on the use of robotic devices have recently shown to provide promising clinical results. However, their efficacy is still limited because of the poor comprehension of the mechanisms at the basis of functional ...

Sage Publications Inc2014

EMG-based pattern recognition approach in post stroke robot-aided rehabilitation: a feasibility study

Silvestro Micera

Background: Several studies investigating the use of electromyographic (EMG) signals in robot-based stroke neurorehabilitation to enhance functional recovery. Here we explored whether a classical EMG-based patterns recognition approach could be employed to ...

BioMed Central2013

How the selection of muscles influences their synergies? A preliminary study using real data

Matteo Mancuso, Elvira Pirondini, Silvestro Micera, Andrea Crema, Martina Coscia

Muscle synergies have been proposed as building blocks that simplify the construction of movements, and as a method to study motor behavior. However, the pre-processing of the EMG signals and the factorization algorithm may impact on their extraction and m ...

Ieee2013

Soft Robot for Gait Rehabilitation of Spinalized Rodents

Silvestro Micera, Jamie Paik, Grégoire Courtine, Yi Sun, Joachim von Zitzewitz, Rubia van den Brand, Yun Seong Song

Soft actuators made of highly elastic polymers allow novel robotic system designs, yet application-specific soft robotic systems are rarely reported. Taking notice of the characteristics of soft pneumatic actuators (SPAs) such as high customizability and l ...

Ieee2013

Personalized neuroprosthetics

José del Rocio Millán Ruiz, Silvestro Micera, Grégoire Courtine, David Allenson Borton

Decades of technological developments have populated the field of neuroprosthetics with myriad replacement strategies, neuromodulation therapies, and rehabilitation procedures to improve the quality of life for individuals with neuromotor disorders. Despit ...

American Association for the Advancement of Science2013

Cell Guidance on Nanogratings: A Computational Model of the Interplay between PC12 Growth Cones and Nanostructures

Silvestro Micera

Background: Recently, the effects of nanogratings have been investigated on PC12 with respect to cell polarity, neuronal differentiation, migration, maturation of focal adhesions and alignment of neurites. Methodology/Principal Findings: A synergistic proc ...

Public Library Science2013

Surface Modification of Polyimide Thin Films for Peripheral Invasive Neural Interfaces

Silvestro Micera

Despite recognized as one key component for establishing a functional electrical connection with nerves, neural invasive peripheral interfaces are still not optimal for long-term applications in humans. An improvement in the field of biocompatible and nont ...

Asme2013

MUNDUS project: MUltimodal Neuroprosthesis for daily Upper limb Support

Silvestro Micera, Andrea Crema, Claudia Casellato

Background: MUNDUS is an assistive framework for recovering direct interaction capability of severely motor impaired people based on arm reaching and hand functions. It aims at achieving personalization, modularity and maximization of the user's direct inv ...

BioMed Central2013

Neural Engineering: An Exciting, Multi-Disciplinary, and Revolutionary Research Field

Silvestro Micera

Ieee-Inst Electrical Electronics Engineers Inc2013

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