Publications de Margaux Catherine Marie Duchamp

Publications associées (7)

Microfluidic devices for the study of cell-cell, cell-particle and particle-particle interactions

Microfluidics and microtechnologies are of great interest for biological applications. This interest is linked to the fact that microtechnologies enable the study of single cells at the cellular and sub-cellular level. One of many applications of such sing ...

EPFL2020

Toward Microfluidic Label-Free Isolation and Enumeration of Circulating Tumor Cells from Blood Samples

Philippe Renaud, Margaux Catherine Marie Duchamp, Benoît Xavier Emmanuel Desbiolles, Camille Alice Raillon

The isolation, analysis, and enumeration of circulating tumor cells (CTCs) from cancer patient blood samples are a paradigm shift for cancer patient diagnosis, prognosis, and treatment monitoring. Most methods used to isolate and enumerate these target cel ...

WILEY2019

Feedback-free microfluidic oscillator with impinging jets

Philippe Renaud, François Gallaire, Arnaud Bertsch, Alessandro Bongarzone, Margaux Catherine Marie Duchamp

The present paper describes a microfluidic oscillator based on facing impinging jets and operating in laminar flow conditions. Using appropriate microchannel configurations, pulsatile liquid flows are generated at the microscale from steady and equal inlet ...

2020

Method and system for determining intracellular mediators' activity

Philippe Renaud, Horst Arthur Vogel, Thamani Dahoun, Margaux Catherine Marie Duchamp, Marc Brugarolas Campillos

A method for determining the presence of a molecule coupled to the cytoplasmic side of a cellular membrane is disclosed. The method is implemented in a microfluidic setting and is particularly suitable for determining the presence and/or the activity of a ...

2022

Microfluidic device performing on flow study of serial cell–cell interactions of two cell populations

Clarisse Jeanne Antonia Benoit, Philippe Renaud, George Coukos, Alexandre Harari, Thamani Dahoun, Margaux Catherine Marie Duchamp

In this study we present a novel microfluidic hydrodynamic trapping device to probe the cell–cell interaction between all cell samples of two distinct populations. We have exploited an hydrodynamic trapping method using microfluidics to immobilize a batch ...

2019

Microfluidic Device for Droplet Pairing by Combining Droplet Railing and Floating Trap Arrays

Philippe Renaud, George Coukos, Alexandre Harari, Margaux Catherine Marie Duchamp

Droplet microfluidics are characterized by the generation and manipulation of discrete volumes of solutions, generated with the use of immiscible phases. Those droplets can then be controlled, transported, analyzed or their content modified. In this wide d ...

MDPI2021

Biotechnologies to tackle the challenge of neoantigen identification

Philippe Renaud, George Coukos, Alexandre Harari, Margaux Catherine Marie Duchamp

Among immune correlates of clinical responses, tumor-specificneoantigens took the spotlight as relevant targets for cancerimmunotherapy. The implementation of pipelines forpersonalized cancer therapy remains challenging due to theprivacy, that is patient-s ...

2020