Nicola Harris

Cette personne a quitté l’EPFL

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Publications associées (53)

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HVEM Signalling Promotes Colitis

Nicola Harris

Tumor necrosis factor super family (TNFSF) members regulate important processes involved in cell proliferation, survival and differentiation and are therefore crucial for the balance between homeostasis and inflammatory responses. Several members of the TN ...

Public Library of Science2011

CMOS and 3D Printing for NMR Spectroscopy at the Single Embryo Scale

Martinus Adela Maria Gijs, Jürgen Brugger, Giovanni Boero, Nicola Harris, Johann Michler, Franck Vincent, Marco Grisi, Beatrice Volpe, Maria Cristina Letizia, Laszlo Pethö, Enrica Montinaro

SWISS CHEMICAL SOC2019

Understanding the role of antibodies in murine infections with Heligmosomoides (polygyrus) bakeri: 35 years ago, now and 35 years ahead

Nicola Harris

The rodent intestinal nematode H.p.bakeri has played an important role in the exploration of the host–parasite relationship of chronic nematode infections for over six decades, since the parasite was first isolated in the 1950s by Ehrenford. It soon became ...

Wiley-Blackwell2014

Parasite Proximity Drives the Expansion of Regulatory T Cells in Peyer's Patches following Intestinal Helminth Infection

Nicola Harris, Beatrice Volpe, Julia Esser-von Bieren, Mario Michael Zaiss, Lalit Kumar Dubey, Ilaria Mosconi, Luc Xavier Marie Lebon

Helminth infections are typically chronic in nature; however, the exact molecular mechanisms by which these parasites promote or thwart host immunity remain unclear. Worm expulsion requires the differentiation of CD4(+) T cells into Th2 cells, while regula ...

American Society for Microbiology2015

Only Two Can Tango: Mast Cells Displace Epithelial Cells to Dance with ILC2s

Nicola Harris, Tiffany Babette Angélique Bouchery

Mast cells have been implicated in protective immunity to helminth infection, but the precise mechanism remains unclear. In this issue of Immunity, Shimokawa et al., 2017 report that mast cells are a bridge linking dying epithelial cells with effector type ...

Elsevier2017

Skin microbiome, skin barrier, and atopic dermatitis in the first year of life

Nicola Harris

WILEY2020

Intestinal bacteria induce TSLP to promote mutualistic T-cell responses

Nicola Harris, Mario Michael Zaiss, Ilaria Mosconi

Thymic stromal lymphopoietin (TSLP) is constitutively expressed in the intestine and is known to regulate inflammation in models of colitis. We show that steady-state TSLP expression requires intestinal bacteria and has an important role in limiting the ex ...

Nature Publishing Group2013

IMMUNOLOGY Chronic effects of acute infections

Nicola Harris

Acute infection of mice with an intestinal pathogen leads to long-lasting inflammation that is maintained by intestinal microorganisms. This observation reveals a path by which infection history can affect long-term immune function. ...

Nature Publishing Group2015

Exploiting Old Pathogens to Create New Therapeutics

Nicola Harris, Tiffany Babette Angélique Bouchery

Intestinal worms are well known for their potent immuno-modulatory capacity. In a recent study, Navarro et al. (2016) identify a secreted hookworm protein that can suppress allergic responses in both mice and humans. This represents an exciting strategy fo ...

Cell Press2016

Nicola Harris

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HVEM Signalling Promotes Colitis

CMOS and 3D Printing for NMR Spectroscopy at the Single Embryo Scale

Understanding the role of antibodies in murine infections with Heligmosomoides (polygyrus) bakeri: 35 years ago, now and 35 years ahead

Parasite Proximity Drives the Expansion of Regulatory T Cells in Peyer's Patches following Intestinal Helminth Infection

Only Two Can Tango: Mast Cells Displace Epithelial Cells to Dance with ILC2s

Skin microbiome, skin barrier, and atopic dermatitis in the first year of life

Intestinal bacteria induce TSLP to promote mutualistic T-cell responses

IMMUNOLOGY Chronic effects of acute infections

Exploiting Old Pathogens to Create New Therapeutics

Age-dependent regulation of remodeling factors during allergic airway inflammation

Dialogue Between Neutrophils And Hookworms Determines Parasite Development

NMR spectroscopy of subnanoliter ova with ultra-compact inductive probes

IMMUNOLOGY. The enigmatic tuft cell in immunity