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Lorenzo Mari

Cette personne a quitté l’EPFL

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Publications associées (46)

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Modeling Key Drivers of Cholera Transmission Dynamics Provides New Perspectives for Parasitology

Andrea Rinaldo, Enrico Bertuzzo, Melanie Blokesch, Lorenzo Mari

Hydroclimatological and anthropogenic factors are key drivers of waterborne disease transmission. Information on human settlements and host mobility on waterways along which pathogens and hosts disperse, and relevant hydroclimatological processes, can be a ...

2017

Modelled effects of prawn aquaculture on poverty alleviation and schistosomiasis control

Andrea Rinaldo, Lorenzo Mari, Francisco Javier Perez Saez

Recent evidence suggests that snail predators may aid efforts to control the human parasitic disease schistosomiasis by eating aquatic snail species that serve as intermediate hosts of the parasite. Here, potential synergies between schistosomiasis control ...

NATURE PUBLISHING GROUP2019

Cholera in the Lake Kivu region (DRC): Integrating remote sensing and spatially explicit epidemiological modeling

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Flavio Finger, Allyn Christine Knox

Mathematical models of cholera dynamics can not only help in identifying environmental drivers and processes that influence disease transmission, but may also represent valuable tools for the prediction of the epidemiological patterns in time and space as ...

American Geophysical Union2014

Optimizing a remotely sensed proxy for plankton biomass in Lake Kivu

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Allyn Christine Knox

Many regions of the world, including inland lakes, present with suboptimal conditions for the remotely sensed retrieval of optical signals, thus challenging the limits of available satellite data-processing tools, such as atmospheric correction models (ACM ...

Taylor & Francis2014

Hydrology and density feedbacks control the ecology of intermediate hosts of schistosomiasis across habitats in seasonal climates

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Natalie Claire Ceperley, Francisco Javier Perez Saez, Theophile Mande

We report about field and theoretical studies on the ecology of the aquatic snails (Bulinus spp. and Biomphalaria pfeifferi) that serve as obligate intermediate hosts in the complex life cycle of the parasites causing human schistosomiasis. Snail abundance ...

Natl Acad Sciences2016

Spread and dynamics of the COVID-19 epidemic in Italy: Effects of emergency containment measures

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Luca Carraro

The spread of coronavirus disease 2019 (COVID-19) in Italy prompted drastic measures for transmission containment. We examine the effects of these interventions, based on modeling of the unfolding epidemic. We test modeling options of the spatially explici ...

National Academy of Sciences2020

Modelling cholera epidemics: the role of waterways, human mobility and sanitation

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto

We investigate the role of human mobility as a driver for long-range spreading of cholera infections, which primarily propagate through hydrologically controlled ecological corridors. Our aim is to build a spatially explicit model of a disease epidemic, wh ...

2012

On the probability of extinction of the Haiti cholera epidemic

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Flavio Finger

More than three years after its appearance in Haiti, cholera has already caused more than 8,500 deaths and 695,000 infections and it is feared to become endemic. However, no clear evidence of a stable environmental reservoir of pathogenic Vibrio cholerae, ...

Springer Verlag2016

Metapopulation persistence and species spread in river networks

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari

River networks define ecological corridors characterised by unidirectional streamflow, which may impose downstream drift to aquatic organisms or affect their movement. Animals and plants manage to persist in riverine ecosystems, though, which in fact harbo ...

Wiley-Blackwell2014

Integration of satellite remote sensing data in ecosystem modelling at local scales: Practices and trends

Andrea Rinaldo, Lorenzo Mari, Damiano Pasetto

2018

Spatially explicit effective reproduction numbers from incidence and mobility data

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Damiano Pasetto, Cristiano Trevisin

Current methods for near real-time estimation of effective reproduction numbers from surveillance data overlook mobility fluxes of infectors and susceptible individuals within a spatially connected network (the metapopulation). Exchanges of infections amon ...

2023

Geomorphic controls on elevational gradients of species richness

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Florian Altermatt, Francesco Carrara

Elevational gradients of biodiversity have been widely investigated, and yet a clear interpretation of the biotic and abiotic factors that determine how species richness varies with elevation is still elusive. In mountainous landscapes, habitats at differe ...

Natl Acad Sciences2016

Epidemicity of cholera spread and the fate of infection control measures

Andrea Rinaldo, Lorenzo Mari, Damiano Pasetto, Joseph Chadi Benoit Lemaitre, Cristiano Trevisin

The fate of ongoing infectious disease outbreaks is predicted through reproduction numbers, defining the long-term establishment of the infection, and epidemicity indices, tackling the reactivity of the infectious pool to new contagions. Prognostic metrics ...

2022

Floquet theory for seasonal environmental forcing of spatially explicit waterborne epidemics

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari

The transmission of waterborne pathogens is a complex process that is heavily linked to the spatial characteristics of the underlying environmental matrix as well as to the temporal variability of the relevant hydroclimatological drivers. In this work, we ...

Springer Heidelberg2014

The geography of COVID-19 spread in Italy and implications for the relaxation of confinement measures

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Damiano Pasetto

The pressing need to restart socioeconomic activities locked-down to control the spread of SARS-CoV-2 in Italy must be coupled with effective methodologies to selectively relax containment measures. Here we employ a spatially explicit model, properly atten ...

Nature Research2020

Heterogeneity in schistosomiasis transmission dynamics

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Francisco Javier Perez Saez

Simple models of disease propagation often disregard the effects of transmission heterogeneity on the ecological and epidemiological dynamics associated with host-parasite interactions. However, for some diseases like schistosomiasis, a widespread parasiti ...

Academic Press Ltd- Elsevier Science Ltd2017

Rainfall mediations in the spreading of epidemic cholera

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto

Following the empirical evidence of a clear correlation between rainfall events and cholera resurgence that was observed in particular during the recent outbreak in Haiti, a spatially explicit model of epidemic cholera is re-examined. Specifically, we test ...

Elsevier Sci Ltd2013

Detection of Vibrio cholerae O1 and O139 in environmental waters of rural Bangladesh: a flow-cytometry-based field trial

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Lorenzo Righetto

Presence of Vibrio cholerae serogroups O1 and O139 in the waters of the rural area of Matlab, Bangladesh, was investigated with quantitative measurements performed with a portable flow cytometer. The relevance of this work relates to the testing of a field ...

Cambridge University Press2015

Hydrologic Variability Affects Invertebrate Grazing on Phototrophic Biofilms in Stream Microcosms

Andrea Rinaldo, Tom Ian Battin, Enrico Bertuzzo, Lorenzo Mari, Serena Ceola

The temporal variability of streamflow is known to be a key feature structuring and controlling fluvial ecological communities and ecosystem processes. Although alterations of streamflow regime due to habitat fragmentation or other anthropogenic factors ar ...

Public Library of Science2013

The temporal patterns of disease severity and prevalence in schistosomiasis

Andrea Rinaldo, Lorenzo Mari

Schistosomiasis is one of the most widespread public health problems in the world. In this work, we introduce an eco-epidemiological model for its transmission and dynamics with the purpose of explaining both intra-and inter-annual fluctuations of disease ...

American Institute of Physics2015