Publications de Alexis Roche | EPFL Graph Search

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Objective Mild neurocognitive disorders (MND) affect a subset of HIV+ patients under effective combination antiretroviral therapy (cART). In this study, we used an innovative multi-contrast magnetic resonance imaging (MRI) approach at high-field to assess ...

Background and objectives: The thalamus exerts a pivotal role in pain processing and cortical excitability control, and migraine is characterized by repeated pain attacks and abnormal cortical habituation to excitatory stimuli. This work aimed at studying ...

Introduction. Local microstructural pathology in multiple sclerosis patients might influence their clinical performance. This study applied multicontrast MRI to quantify inflammation and neurodegeneration in MS lesions. We explored the impact of MRI-based ...

Purpose To suppress the noise, by sacrificing some of the signal homogeneity for numerical stability, in uniform T1 weighted (T1w) images obtained with the magnetization prepared 2 rapid gradient echoes sequence (MP2RAGE) and to compare the clinical utilit ...

Objectives: The aim of this study was to study focal cerebellar pathology in early stages of multiple sclerosis (MS) using ultra-high-field magnetization-prepared 2 inversion-contrast rapid gradient-echo (7T MP2RAGE). Materials and Methods: Twenty early-st ...

Background: Cerebellar pathology occurs in late multiple sclerosis (MS) but little is known about cerebellar changes during early disease stages. In this study, we propose a new multicontrast “connectometry” approach to assess the structural and functional ...

The involvement of the cerebellum in migraine pathophysiology is not well understood. We used a biparametric approach at high-field MRI (3 T) to assess the structural integrity of the cerebellum in 15 migraineurs with aura (MWA), 23 migraineurs without aur ...

The cerebellum is involved in multiple sclerosis (MS), but its implication in early phases is still poorly understood. We investigated structural and functional cerebellar connectivity alterations in early and minimally impaired MS patients, and their corr ...

Inference of Markov random field images segmentation models is usually performed using iterative methods which adapt the well-known expectation-maximization (EM) algorithm for independent mixture models. However, some of these adaptations are ad-hoc and ma ...

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer's disease (AD) related brain atrophy and to enable accurate automated classification of AD patients, mild cognitive impaired (MCI) patients and elderly ...

Conventional magnetic resonance imaging (MRI) measures of multiple sclerosis patients provide limited information about the nature and the extent of brain damage and repair. We established a clinically compatible protocol including quantitative MRI techniq ...

Conventional magnetic resonance imaging (MRI) of patients with multiple sclerosis provides only limited insights into the nature of brain tissue damage with modest clinical-radiological correlations. In this study, quantitative and semi-quantitative MRI te ...

Disclosed is a Magnetic Resonance Imaging method comprising the steps of: generating an MRI sequence designed for acquiring data from an object to be imaged, wherein the MRI sequence is configured for generating at least two different standard images, resp ...

Objectives: In this study, we investigated the structural plasticity of the contralesional motor network in ischemic stroke patients using diffusion magnetic resonance imaging (MRI) and explored a model that combines a MRI-based metric of contralesional ne ...

In patients with multiple sclerosis (MS), conventional magnetic resonance imaging (MRI) provides only limited insights into the nature of brain damage with modest clinic-radiological correlation. In this study, we applied recent advances in MRI techniques ...

Alexis Roche

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Micro-Structural Brain Alterations in Aviremic HIV+ Patients with Minor Neurocognitive Disorders: A Multi-Contrast Study at High Field

Structural abnormalities in the thalamus of migraineurs with aura: a multiparametric study at 3T

Multicontrast MRI Quantification of Focal Inflammation and Degeneration in Multiple Sclerosis

Robust T1-Weighted Structural Brain Imaging and Morphometry at 7T Using MP2RAGE

An Ultra-High Field Study of Cerebellar Pathology in Early Relapsing-Remitting Multiple Sclerosis Using MP2RAGE

Multicontrast connectometry: A new tool to assess cerebellum alterations in early relapsing‐remitting multiple sclerosis

Migraineurs without aura show microstructural abnormalities in the cerebellum and frontal lobe

Cerebellar Connectomics Provide New Biomarkers in Early Multiple Sclerosis

On the Convergence of EM-Like Algorithms for Image Segmentation using Markov Random Fields

Volume-based vs. voxel-based brain morphometry in Alzheimer's disease prediction

Multiple Sclerosis Lesion Fingerprint Using Multicontrast MRI

Multicontrats MRI Improved the Clinico-Radiological Correlation in Early Multiple Sclerosis Patients with Minor Deficits

Microstructural alterations in the brain of well treated HIV+ patients with minor neurocognitive disorders: a multi-contrast MRI study at 3T

A simple method to denoise ratio images in magnetic resonance imaging

Structural abnormalities in the thalamus of migraine patients: a multi-parametric study at high field

Personalized pathology maps to quantify diffuse and focal brain damage

A new early and automated MRI-based predictor of motor improvement after stroke

A simple method to denoise MP2RAGE

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis

Microstructural alterations in the brain of well treated HIV+ patients with minor neurocognitive disorders: a multi-contrast study at high field