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Josefina Adriana Maria Bastiaansen

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Publications associées (46)

Radical-free mixture of co-polarized 13C metabolites for probing separate biochemical pathways in vivo by hyperpolarized 13C MR

Arnaud Comment, Rolf Gruetter, Josefina Adriana Maria Bastiaansen, Andrea Capozzi, Hikari Ananda Infinity Yoshihara

2015

Myocardial fatty acid metabolism probed with hyperpolarized [1-13C]octanoate

Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara

2015

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

Arnaud Comment, Rolf Gruetter, Josefina Adriana Maria Bastiaansen, Yuhei Takado, Hikari Ananda Infinity Yoshihara

Resting skeletal muscle has a preference for the oxidation of lipids compared to carbohydrates and a shift towards carbohydrate oxidation is observed with increasing exercise. Lactate is not only an end product in skeletal muscle but also an important meta ...

2014

Assessing energy metabolism in the ischemic rat heart with hyperpolarized 13C pyruvate

Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara

2014

Measuring In Vivo Myocardial Substrate Competition Using Hyperpolarized 13C Magnetic Resonance

Arnaud Comment, Josefina Adriana Maria Bastiaansen

2014

Assessing Energy Metabolism In The Ischemic Rat Heart With Hyperpolarized C-13 Pyruvate

Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara

2014

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

Arnaud Comment, Rolf Gruetter, Josefina Adriana Maria Bastiaansen, Yuhei Takado, Hikari Ananda Infinity Yoshihara

2014

Probing energy metabolism in the ischemic rat heart with hyperpolarized 13C MRS

Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara

2014

Metabolic flux analysis of acetylcarnitine turnover and mitochondrial oxidation of [2-13C]acetate in rat skeletal muscle in vivo measured by 13C MRS

Rolf Gruetter, João Miguel das Neves Duarte, Josefina Adriana Maria Bastiaansen

2014

Assessing energy metabolism non-invasively in the ischemic-reperfused rat heart with hyperpolarized C-13 pyruvate

Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara

2014

Automated transfer and injection of hyperpolarized molecules with polarization measurement prior to in vivo NMR

Arnaud Comment, Mor-Miri Mishkovsky, Tian Cheng, Josefina Adriana Maria Bastiaansen

Hyperpolarized magnetic resonance via dissolution dynamic nuclear polarization necessitates the transfer of the hyperpolarized molecules from the polarizer to the imager prior to in vivo measurements. This process leads to unavoidable losses in nuclear pol ...

2013

In vivo metabolic studies in skeletal and cardiac muscle using ¹³C magnetic resonance spectroscopy

Josefina Adriana Maria Bastiaansen

Cardiac and skeletal muscle function relies on a continuous energy production via fatty acid metabolism and mitochondrial oxidation of pyruvate, with a fine balance between substrate delivery and utilization. Changes in metabolism are increasingly being im ...

EPFL2013

Acetylcarnitine turnover in rat skeletal muscle measured in vivo using localized 13C NMR at 14.1 T

Arnaud Comment, Rolf Gruetter, João Miguel das Neves Duarte, Josefina Adriana Maria Bastiaansen

2013

Energy metabolism in the ischemic rat heart assessed using hyperpolarized 13C

Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara

2013

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

Arnaud Comment, Rolf Gruetter, João Miguel das Neves Duarte, Mor-Miri Mishkovsky, Tian Cheng, Josefina Adriana Maria Bastiaansen

BACKGROUND: Acetate metabolism in skeletal muscle is regulated by acetylCoA synthetase (ACS). The main function of ACS is to provide cells with acetylCoA, a key molecule for numerous metabolic pathways including fatty acid and cholesterol synthesis and the ...

Elsevier Science Bv2013

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Josefina Adriana Maria Bastiaansen

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Radical-free mixture of co-polarized 13C metabolites for probing separate biochemical pathways in vivo by hyperpolarized 13C MR

Myocardial fatty acid metabolism probed with hyperpolarized [1-13C]octanoate

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

Assessing energy metabolism in the ischemic rat heart with hyperpolarized 13C pyruvate

Measuring In Vivo Myocardial Substrate Competition Using Hyperpolarized 13C Magnetic Resonance

Assessing Energy Metabolism In The Ischemic Rat Heart With Hyperpolarized C-13 Pyruvate

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

Probing energy metabolism in the ischemic rat heart with hyperpolarized 13C MRS

Metabolic flux analysis of acetylcarnitine turnover and mitochondrial oxidation of [2-13C]acetate in rat skeletal muscle in vivo measured by 13C MRS

Assessing energy metabolism non-invasively in the ischemic-reperfused rat heart with hyperpolarized C-13 pyruvate

Automated transfer and injection of hyperpolarized molecules with polarization measurement prior to in vivo NMR

In vivo metabolic studies in skeletal and cardiac muscle using ¹³C magnetic resonance spectroscopy

Acetylcarnitine turnover in rat skeletal muscle measured in vivo using localized 13C NMR at 14.1 T

Energy metabolism in the ischemic rat heart assessed using hyperpolarized 13C

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

Hyperpolarized [1-13C]lactate metabolism in rat skeletal muscle in vivo

Hyperpolarized [1-13C]acetylcarnitine as a tracer for cardiac metabolism

In vivo enzymatic assay of carnitine acetyl transferase and acetylCoA synthetase using hyperpolarized acetate

In vivo real time cardiac metabolism using hyperpolarized acetate

Kinetic analysis of acetylCoA synthetase activity in skeletal muscle