Tian Cheng

Cette personne n’est plus à l’EPFL

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Publications associées (102)

Over 35% liquid-state 13C polarization via dissolution dynamic nuclear polarization at 7 T and 1 K with ubiquitous nitroxyl radicals

Arnaud Comment, Riccardo Balzan, Tian Cheng, Yuhei Takado, Andrea Capozzi

The most versatile method to increase liquid-state 13C NMR sensitivity is dissolution dynamic nuclear polarization. The use of trityl radicals is usually required to obtain very large 13C polarization via this technique. We herein demonstrate that up to 35 ...

Royal Soc Chemistry2013

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

Arnaud Comment, Rolf Gruetter, João Miguel das Neves Duarte, Mor-Miri Mishkovsky, Tian Cheng, Josefina Adriana Maria Bastiaansen

BACKGROUND: Acetate metabolism in skeletal muscle is regulated by acetylCoA synthetase (ACS). The main function of ACS is to provide cells with acetylCoA, a key molecule for numerous metabolic pathways including fatty acid and cholesterol synthesis and the ...

Elsevier Science Bv2013

Over 35% of liquid-state 13C polarization enhanced by TEMPOL via high field dissolution dynamic nuclear polarization

Arnaud Comment, Riccardo Balzan, Tian Cheng, Yuhei Takado, Andrea Capozzi

2013

Hyperpolarization without persistent radicals for in vivo real-time metabolic imaging

Arnaud Comment, Christophe Roussel, Mor-Miri Mishkovsky, Tian Cheng, Tim Rolf Eichhorn, Yuhei Takado, Jean-Noël Hyacinthe, Najat Salameh, Andrea Capozzi

Hyperpolarized substrates prepared via dissolution dynamic nuclear polarization have been proposed as magnetic resonance imaging (MRI) agents for cancer or cardiac failure diagnosis and therapy monitoring through the detection of metabolic impairments in v ...

National Academy of Sciences2013

Hyperpolarized [1-13C]acetylcarnitine as a tracer for cardiac metabolism

Arnaud Comment, Rolf Gruetter, Tian Cheng, Josefina Adriana Maria Bastiaansen

2013

Localized in vivo hyperpolarization transfer sequences

Arnaud Comment, Rolf Gruetter, Mor-Miri Mishkovsky, Tian Cheng

In vivo localized and fully adiabatic homonuclear and heteronuclear polarization transfer experiments were designed and performed in the rat brain at 9.4 T after infusion of hyperpolarized sodium [1,2-(13) C(2) ] and sodium [1-(13) C] acetate. The method p ...

Wiley-Blackwell2012

Development and characterization of an automated dissolution-DNP setup for in vivo hyperpolarized MRS and MRI in rodent at 14.1T

Arnaud Comment, Jacques Van Der Klink, Riccardo Balzan, Tian Cheng

2011

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Tian Cheng

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Over 35% liquid-state 13C polarization via dissolution dynamic nuclear polarization at 7 T and 1 K with ubiquitous nitroxyl radicals

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

Over 35% of liquid-state 13C polarization enhanced by TEMPOL via high field dissolution dynamic nuclear polarization

Hyperpolarization without persistent radicals for in vivo real-time metabolic imaging

Hyperpolarized [1-13C]acetylcarnitine as a tracer for cardiac metabolism

Localized in vivo hyperpolarization transfer sequences

In vivo enzymatic assay of carnitine acetyl transferase and acetylCoA synthetase using hyperpolarized acetate

A comparison of high-pass birdcage coils for small animal imaging at 9.4 and 14T

In vivo real time cardiac metabolism using hyperpolarized acetate

Kinetic analysis of acetylCoA synthetase activity in skeletal muscle

Producing radical-free hyperpolarized solutions for in vivo magnetic resonance

Method to minimize the polarization losses in hyperpolarized biomolecules prior to in vivo MR experiments

BDPA as a polarizing agent for in vivo hyperpolarized MR experiment

Development and characterization of an automated dissolution-DNP setup for in vivo hyperpolarized MRS and MRI in rodent at 14.1T

Localized in vivo hyperpolarization transfer experiments

The metabolic effect of hyperpolarized [1-13C]acetate dosage in vivo

In vivo localized 15N MRS detection of hyperpolarized 15N labeled choline in the rat brain

In vivo real-time metabolic studies of mice brain and skeletal muscle at 9.4T

Study of acetylcarnitine kinetics in skeletal muscle in vivo using hyperpolarized 1-13C acetate

Hyperpolarized acetate as a metabolic tracer for skeletal and cardiac muscle energetics