Publications de Zaïnebe Dhirani

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Agrobacterium tumefaciens is a plant pathogen commonly repurposed for genetic modification of crops. Despite its versatility, it remains inefficient at transferring DNA to many hosts, including to animal cells. Like many pathogens, physical contact between ...

During chronic infections and in microbiota, bacteria predominantly colonize their hosts as multicellular structures called biofilms. A common assumption is that biofilms exclusively interact with their hosts biochemically. However, the contributions of me ...

The opportunistic pathogen Pseudomonas aeruginosa adapts to solid surfaces to enhance virulence and infect its host. Type IV pili (T4P), long and thin filaments that power surface-specific twitching motility, allow single cells to sense surfaces and contro ...

Pathogen attachment to host tissue is critical in the progress of many infections. Bacteria use adhesion in vivo to stabilize colonization and subsequently regulate the deployment of contact-dependent virulence traits. To specifically target host cells, th ...

The opportunistic pathogen Pseudomonas aeruginosa explores surfaces using twitching motility powered by retractile extracellu-lar filaments called type IV pili (T4P). Single cells twitch by sequen-tial T4P extension, attachment, and retraction. How single ...

Zaïnebe Dhirani

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Engineering Agrobacterium tumefaciens Adhesion to Target Cells

Biofilms deform soft surfaces and disrupt epithelia

Two antagonistic response regulators control Pseudomonas aeruginosa polarization during mechanotaxis

The Mammalian Membrane Microenvironment Regulates the Sequential Attachment of Bacteria to Host Cells

Mechanotaxis directs Pseudomonas aeruginosa twitching motility