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Ye Pu

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Publications associées (32)

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Characterization of the cytotoxicity and imaging properties of secondharmonic nanoparticles

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu

We develop second-harmonic nanoparticles as the contrast agents for cell imaging. Second-harmonic nanoparticles show promise as cell imaging probes due to their non-bleaching, non-blinking, and coherent signal. Nanoparticles of noncentrosymmetric crystal s ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2010

Imaging with second-harmonic radiation probes in living tissue

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu, Thomas Jean Victor Marie Lanvin

We demonstrate that second-harmonic radiation imaging probes are efficient biomarkers for imaging in living tissue. We show that 100 nm and 300 nm BaTiO3 nanoparticles used as contrast markers could be detected through 50 mu m and 120 mu m of mouse tail ti ...

2011

Hollow Mesoporous Plasmonic Nanoshells for Enhanced Solar Vapor Generation

Demetri Psaltis, Jeffrey Alan Hubbell, Ye Pu, Ye Pu, Jae-Woo Choi, Miguel Antonio Modestino, Seyyed Mohammad Hosseini Hashemi, Marcin Stefan Zielinski, Thomas La Grange

In the past decade, nanomaterials have made their way into a variety of technologies in solar energy, enhancing the performance by taking advantage of the phenomena inherent to the nanoscale. Recent examples exploit plasmonic core/shell nanoparticles to ac ...

American Chemical Society2016

Modulational instability in nonlinearity-managed optical media

Demetri Psaltis, Ye Pu, Ye Pu

We investigate analytically, numerically, and experimentally the modulational instability in a layered, cubically nonlinear (Kerr) optical medium that consists of alternating layers of glass and air. We model this setting using a nonlinear Schrödinger (NLS ...

2007

Nonlinear optical properties of core-shell nanocavities for enhanced second-harmonic generation

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu

A nonlinear optical plasmonic core-shell nanocavity is demonstrated as an efficient, subwavelength coherent light source through second-harmonic generation. The nonlinear optical plasmonic nanocavity incorporates a noncentrosymmetric medium, which utilizes ...

2010

Second-harmonic radiating imaging probes and harmonic holography

Demetri Psaltis, Ye Pu, Ye Pu

Compared with other imaging probes such as fluorescent dyes and quantum dots, second-harmonic radiating imaging probes (SHRIMPs) provide a unique ultrafast, coherent optical contrast that is free of photobleaching and emission intermittency. Using the seco ...

Spie-Int Soc Optical Engineering2016

Three-dimensional harmonic holographic microcopy using nanoparticles as probes for cell imaging

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu

Luminescent markers play a key role in imaging techniques for life science since they provide a contrast mechanism between signal and background. We describe a new type of marker using second harmonic generation (SHG) from noncentrosymmetric BaTiO3 nanocry ...

Optical Society of America2009

Barium titanate nanoparticles used as second harmonic radiation imaging probes for cell imaging

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu

2009

Second harmonic generation from nanocrystals under linearly and circularly polarized excitations

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu

We study second harmonic generation (SHG) from noncentrosymmetric nanocrystals under linearly polarized (LP) and circularly polarized (CP) excitations. Theoretical models are developed for SHG from nanocrystals under both plane-wave and focused excitations ...

2010

Digital phase conjugation of second harmonic radiation emitted by nanoparticles in turbid media

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu

We demonstrate focusing coherent light on a nanoparticle through turbid media based on digital optical phase conjugation of second harmonic generation (SHG) field from the nanoparticle. A SHG active nanoparticle inside a turbid medium was excited at the fu ...

2010

Harmonic holography: a new holographic principle

Demetri Psaltis, Ye Pu, Ye Pu

The process of second harmonic generation (SHG) has a unique property of forming a sharp optical contrast between noncentrosymmetric crystalline materials and other types of material, which is a highly valuable asset for contrast microscopy. The coherent s ...

Optical Society of America2008

Two-photon microscopy of the mouse cochlea in situ for cellular diagnosis

Demetri Psaltis, Ye Pu, Chia-Lung Hsieh, Ye Pu, Xin Yang

Sensorineural hearing loss is the most common type of hearing loss worldwide, yet the underlying cause is typically unknown because the inner ear cannot be biopsied today without destroying hearing, and intracochlear cells have not been imaged with resolut ...

SPIE Society of Photo-optical Instrumentation Engineers2013

Second harmonic generating (SHG) Nanoprobes: A new tool for biomedical imaging

Demetri Psaltis, Ye Pu, Ye Pu

Cornea functions as an outermost lens and plays an important role in vision. For cornea diagnosis and treatment, a microscopic imaging system with cellular resolution and high eye safety is strongly desired. Recently, the cell morphology of corneal epithel ...

2009

Imaging blood cells through scattering biological tissue using speckle scanning microscopy

Demetri Psaltis, Ye Pu, Ye Pu, Xin Yang

We demonstrate imaging of blood cells enclosed in chicken skin tissue using speckle scanning microscopy (SSM). Clear images of multiple cells were obtained with subcellular resolution and good image fidelity, provided that the object dimension was smaller ...

Optical Society of America2014

Harmonic holography for three-dimensional cellular imaging

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu

Luminescent markers play a key role in imaging techniques for life sciences since they provide a contrast mechanism between signal and background. We describe a new type of marker using second harmonic generation (SHG) from noncentrosymmetric BaTiO3 nanocr ...

2009

Harmonic Holography

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu

2010

Bioconjugation of barium titanate nanocrystals with immunoglobulin G antibody for second harmonic radiation imaging probes

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh, Ye Pu

The second harmonic generation (SHG) active nanocrystals have been demonstrated as attractive imaging probes in nonlinear microscopy due to their coherent, non-bleaching and non-blinking signals with a broad flexibility in the choice of excitation waveleng ...

Elsevier2010

Fabrication of Sub-Micron Polymer Waveguides through Two-Photon Polymerization in Polydimethylsiloxane

Demetri Psaltis, Christophe Moser, Ye Pu, Giulia Panusa, Jieping Wang

Flexible ultra-compact low-loss optical waveguides play a vital role in the development of soft photonics. The search for suitable materials and innovative fabrication techniques to achieve low loss long polymer optical waveguides and interconnects has pro ...

2020

Two-dimensional polymeric structures and method for producing thereof

Demetri Psaltis, Jeffrey Alan Hubbell, Ye Pu, Ye Pu, Marcin Stefan Zielinski

The present invention relates to polymeric structures, in the form of flat membrane-like surfaces or micro- nanostructures such as capsules, characterized in that it comprises a substantially two-dimensional layer of covalently-bonded monomers of R-substit ...

2016

Three-dimensional scanning microscopy through thin turbid media

Demetri Psaltis, Ye Pu, Chia-Lung Hsieh, Ye Pu, Xin Yang

We demonstrate three-dimensional imaging through a thin turbid medium using digital phase conjugation of the second harmonic signal emitted from a beacon nanoparticle. The digitally phase-conjugated focus scans the volume in the vicinity of its initial pos ...

2012