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Giuseppe Schiavone

Cette personne a quitté l’EPFL

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Publications associées (23)

Page 1 sur 2

Chronic recording of cortical activit y underlying vocalization in awake minipigs

Stéphanie Lacour, Giuseppe Schiavone, Florian Dylan Fallegger

Background: Investigating brain dynamics underlying vocal production in animals is a powerf u l w a y to inform on the neural bases of human speech. In particular, brain networks underlying vocal production in non-human primates show striking similarities ...

ELSEVIER2022

Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury

Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Jocelyne Bloch, Giuseppe Schiavone, Florian Dylan Fallegger, Nicolas Vachicouras, Quentin Barraud, Jordan Squair, Ileana Ozana Jelescu, Eduardo Martin Moraud, Fabien Bertrand Paul Wagner, Robin Jonathan Demesmaeker, Claudia Kathe, Matthieu Pierre Gautier, Mark Andrew Anderson, Newton Cho, Nicholas David James, Salif Axel Komi, Jimmy James Ravier, Jérôme Gandar, Andreas Rowald, Kay Alexander Bartholdi, Charlotte Marie Jacques Moerman, Achilleas Laskaratos, Laura Ann McCracken, Loïs Thomas Romain Mahe, Arnaud Bichat

Spinal cord injury (SCI) induces haemodynamic instability that threatens survival(1-3), impairs neurological recovery(4,5), increases the risk of cardiovascular disease(6,7), and reduces quality of life(8,9). Haemodynamic instability in this context is due ...

NATURE RESEARCH2021

Dimensional scaling of thin-film stimulation electrode systems in translational research

Stéphanie Lacour, Giuseppe Schiavone, Nicolas Vachicouras, Yashwanth Sai Reddy Vyza

Objective. Electrical stimulation of biological tissue is an established technique in research and clinical practice that uses implanted electrodes to deliver electrical pulses for a variety of therapies. Significant research currently explores new electro ...

2021

A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces

Stéphanie Lacour, Giuseppe Schiavone, Florian Dylan Fallegger, Alix Esther Anne Trouillet, Florent-Valéry Coen

Interfacing the human body with the next generation of electronics requires technological advancement in designing and producing bioelectronic circuits. These circuits must integrate electrical functionality while simultaneously addressing limitations in m ...

2023

Conformable Hybrid Systems for Implantable Bioelectronic Interfaces

Stéphanie Lacour, Giuseppe Schiavone, Florian Dylan Fallegger

Conformable bioelectronic systems are promising tools that may aid the understanding of diseases, alleviate pathological symptoms such as chronic pain, heart arrhythmia, and dysfunctions, and assist in reversing conditions such as deafness, blindness, and ...

Wiley2020

Structured nanoscale metallic glass fibres with extreme aspect ratios

Stéphanie Lacour, Grégoire Courtine, Fabien Sorin, Vasiliki Tileli, Giuseppe Schiavone, Wei Yan, Jordan Squair, Yunpeng Qu, Dang Tùng Nguyen, Reinis Ignatans, Güven Kurtuldu, Inès Richard, Nicholas David James

Micro- and nanoscale metallic glasses offer exciting opportunities for both fundamental research and applications in healthcare, micro-engineering, optics and electronics. The scientific and technological challenges associated with the fabrication and util ...

Nature Publishing Group2020

Soft, Implantable Bioelectronic Interfaces for Translational Research

Evgenia Vladimirova Roussinova, Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Jocelyne Bloch, Sébastien Jiguet, Giuseppe Schiavone, Nicolas Vachicouras, Florian Dylan Fallegger, Ivan Furfaro, Xiaoyang Kang, Andreas Rowald, Simon Borgognon, Ismael Seanez Gonzalez

The convergence of materials science, electronics, and biology, namely bioelectronic interfaces, leads novel and precise communication with biological tissue, particularly with the nervous system. However, the translation of lab‐based innovation toward cli ...

Wiley2020

Extended Barrier Lifetime of Partially Cracked Organic/Inorganic Multilayers for Compliant Implantable Electronics

Julien Emile Carron, Yves Leterrier, Stéphanie Lacour, Giuseppe Schiavone, Kyungjin Kim, Kangling Wu

Flexible and soft bioelectronics display conflicting demands on miniaturization, compliance, and reliability. Here, the authors investigate the design and performance of thin encapsulation multilayers against hermeticity and mechanical integrity. Partially ...

WILEY-V C H VERLAG GMBH2021

Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys

Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Giuseppe Schiavone, Florian Dylan Fallegger, Quentin Barraud, Tomislav Milekovic, Katia Galan, Nicholas David James

Regaining arm control is a top priority for people with paralysis. Unfortunately, the complexity of the neural mechanisms underlying arm control has limited the effectiveness of neurotechnology approaches. Here, we exploited the neural function of survivin ...

NATURE PORTFOLIO2022

A modular strategy for next-generation upper-limb sensory-motor neuroprostheses

Silvestro Micera, Solaiman Shokur, Giuseppe Schiavone

Neuroprosthetics is a discipline that aims at restoring lost functions to people affected by a variety of neurological disorders or neuro-traumatic lesions. It combines the expertise of computer science and electrical, mechanical, and micro/nanotechnology ...

ELSEVIER2021

Microscale Liquid Metal Conductors for Stretchable and Transparent Electronics

Stéphanie Lacour, Giuseppe Schiavone, Ivan Furfaro, Laurent Mirko Dejace, Haotian Chen

Integrated wearable electronics capable of transducing and transmitting biophysical information on complex and dynamic systems are attracting high interest across the consumer electronics, clinical, and research domains. Gallium and gallium-based liquid me ...

Wiley2021

Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord

Stéphanie Lacour, Grégoire Courtine, Giuseppe Schiavone, Florian Dylan Fallegger, Nicholas David James, Henri Charles Alexandre Lorach, Simon Borgognon, Nathan Antoine Greiner

Epidural electrical stimulation (EES) of lumbosacral sensorimotor circuits improves leg motor control in animals and humans with spinal cord injury (SCI). Upper-limb motor control involves similar circuits, located in the cervical spinal cord, suggesting t ...

Nature Research2021

Hybrid soft-rigid electrical interconnection system

Stéphanie Lacour, Giuseppe Schiavone, Florian Dylan Fallegger

It is disclosed an electrical interconnection system comprising: i) an interconnection board comprising an intrinsically non elastic substrate, said substrate having a first face and an opposed second face, and at least one conductive track on and/or withi ...

2021

Selective Recruitment of Arm Motoneurons in Nonhuman Primates Using Epidural Electrical Stimulation of the Cervical Spinal Cord

Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Jocelyne Bloch, Giuseppe Schiavone

Recovery of reaching and grasping ability is the priority for people with cervical spinal cord injury (SCI). Epidural electrical stimulation (EES) has shown promising results in improving motor control after SCI in various animal models and in humans. Nota ...

2018

MRI-Compatible and Conformal Electrocorticography Grids for Translational Research

Stéphanie Lacour, Grégoire Courtine, Giuseppe Schiavone, Florian Dylan Fallegger, Fabien Bertrand Paul Wagner, Ludovic Serex

Intraoperative electrocorticography (ECoG) captures neural information from the surface of the cerebral cortex during surgeries such as resections for intractable epilepsy and tumors. Current clinical ECoG grids come in evenly spaced, millimeter-sized elec ...

2021

Long-term functionality of a soft electrode array for epidural spinal cord stimulation in a minipig model

Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Marco Capogrosso, Giuseppe Schiavone, Florian Dylan Fallegger, Nicolas Vachicouras, Fabien Bertrand Paul Wagner, Xiaoyang Kang

Long-term biointegration of man-made neural interfaces is influenced by the mechanical properties of the implant materials. Substantial experimental work currently aims at replacing conventional hard implant materials with soft alternatives that can favour ...

IEEE2018

A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease

Jean François Pierre Laurens, Auke Ijspeert, Silvestro Micera, Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Jocelyne Bloch, Giuseppe Schiavone, Elvira Pirondini, Jordan Squair, Eduardo Martin Moraud, Léonie Asboth, Robin Jonathan Demesmaeker, Tomislav Milekovic, Jimmy James Ravier, Jean-Baptiste Mignardot, Flavio Raschella, Simon Borgognon, Alice Julie Bruel, Carmina Andrea Galvez Solano, Camille Georgette Marie Le Goff-Mignardot, Charlotte Marie Jacques Moerman, David Allenson Borton, Grégory Didier Dumont, Sergio Daniel Hernandez, Nicolò Macellari, Shiqi Sun

People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor deficits that are resistant to currently available therapies. To alleviate these deficits, we developed a neuroprosthesis operating in closed loop that targets the dor ...

Nature Portfolio2023

Automatic clustering of spinal reflexes evoked by epidural electrical stimulation of the cervical spinal cord in non-human primates

Katie Zhi Zhuang, Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Jocelyne Bloch, Giuseppe Schiavone

Epidural electrical stimulation of the spinal cord elicits motor responses by recruiting large sensory afferents in the posterior roots. Divergence of excitatory inputs provided by these fibers generates a variety of shapes, latencies and amplitudes in the ...

2019

Stretchable cuff device

Giuseppe Schiavone, Florian Dylan Fallegger, Nicolas Vachicouras, Ludovic Serex, Valentina Marie Paggi

The invention features a cuff device comprising a support having a first end, a second end and an elongated body in between; connection means for electrical, magnetic and/or fluidic magnetic connection with external devices; at least one of i) an electrode ...

2020

Conformable bioelectronic interfaces: Mapping the road ahead

Stéphanie Lacour, Giuseppe Schiavone

2019