Amalio Telenti

Cette personne n’est plus à l’EPFL

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Publications associées (28)

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A

Amalio Telenti, Jacques Fellay, Paul Jack Mc Laren

Human genetic variation contributes to differences in susceptibility to HIV-1 infection. To search for novel host resistance factors, we performed a genome-wide association study (GWAS) in hemophilia patients highly exposed to potentially contaminated fact ...

Oxford University Press2013

Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

Amalio Telenti, Jacques Fellay, Paul Jack Mc Laren

Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition of HIV-1 after exposure have b ...

Public Library Science2013

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

Amalio Telenti, Jacques Fellay, Istvan Bartha, Paul Jack Mc Laren

HIV-1 sequence diversity is affected by selection pressures arising from host genomic factors. Using paired human and viral data from 1071 individuals, we ran >3000 genome-wide scans, testing for associations between host DNA polymorphisms, HIV-1 sequence ...

Elife Sciences Publications Ltd2013

Addressing the Concerns of the Lacks Family: Quantification of Kin Genomic Privacy

Jean-Pierre Hubaux, Mathias Jacques Jean-Marc Humbert, Amalio Telenti, Erman Ayday

The rapid progress in human-genome sequencing is leading to a high availability of genomic data. This data is notoriously very sensitive and stable in time. It is also highly correlated among relatives. A growing number of genomes are becoming accessible o ...

2013

European genetic diversity and susceptibility to pathogens

Amalio Telenti, Jacques Fellay, Paul Jack Mc Laren

Infectious diseases, both in their endemic and epidemic forms, have shaped the human genome. Ecology has also contributed to geographically constrained pressures on human populations. There are now multiple examples of population-specific genetic variants ...

2013

Analysis of HIV-1 Expression Level and Sense of Transcription by High-Throughput Sequencing of the Infected Cell

Jacques Rougemont, Amalio Telenti

Next-generation sequencing offers an unprecedented opportunity to jointly analyze cellular and viral transcriptional activity without prerequisite knowledge of the nature of the transcripts. SupT1 cells were infected with a vesicular stomatitis virus G env ...

American Society for Microbiology2011

Impact of Phenotype Definition on Genome-Wide Association Signals: Empirical Evaluation in Human Immunodeficiency Virus Type 1 Infection

Amalio Telenti, Jacques Fellay

Oxford University Press2011

The integrase interactor 1 (INI1) proteins facilitate Tat-mediated human immunodeficiency virus type 1 transcription

Didier Trono, Priscilla Turelli, Amalio Telenti

2006

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