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Sandro Carrara

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Publications associées (297)

Chip cleaning and regeneration for electrochemical sensor arrays

Bruno Samori, Sandro Carrara

Sensing systems based on electrochemical detection have generated great interest because electronic readout may replace conventional optical readout in microarray. Moreover, they offer the possibility to avoid labelling for target molecules. A typical elec ...

Elsevier2010

Design of a CNFET Array for Sensing and Control in P450 based Biochips for multiple drug detection

Giovanni De Micheli, Shashi Kanth Bobba, Sandro Carrara

Bio-detection specially dedicated to distributed diagnostics is emerging as a quite important application for Nanobioelectronics. Bio-detection is required to be highly sensitive in order to succeed in sensing small amount of bio-markers in patient’s blood ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2010

Carbon Nanotubes-Based Electrochemical Sensing for Cell Culture Monitoring

Giovanni De Micheli, Cristina Boero, Sandro Carrara, Giovanna Del Vecchio

Monitoring of metabolic compounds, such as glucose and lactate, is extensively reported in literature, especially for clinical purposes. Instead, the application of such technologies for monitoring metabolites in cell cultures has not been explored. From o ...

2010

Characterization of Memristive Poly-Si Nanowires via Empirical Physical Modelling

Giovanni De Micheli, Sandro Carrara

Memristors are passive circuit elements that behave as resistors with memory. The recently illustrated experimental realization of memristive behaviour of Polysilicon Nanowires has triggered interest in this concept, which is promising to a wide variety of ...

2010

Cancer marker detection in human serum with a point-of-care low-cost system

Luca Benini, Sandro Carrara

Chemiluminescence, i.e. the emission of light from a chemical reaction, offers interesting opportunities for developing point-of-care biosensors. However, commercially available systems are expensive, bulky, and primarily addressed to laboratory usage. The ...

2010

New probe immobilizations by lipoate-diethalonamine or ethylene-glycol molecules for capacitance DNA chip

Yusuf Leblebici, Giovanni De Micheli, Bruno Samori, Luca Benini, Andrea Cavallini, Sandro Carrara

Label–free DNA detection is of crucial role to when developing point-of-care biochips to be used in personalized therapy. Capacitance detection is a promising technology for label-free DNA detection. However, data published in literature often show evident ...

2009

Design of an integrated low-noise read-out system for DNA capacitive sensors

Daniela De Venuto, Sandro Carrara

This paper presents an electronic system for a fast DNA label-less detection. The sensitivity of the capacitive sensor in use is improved by depositing an insulating self-assembled monolayer (SAM) over the golden electrodes. The capacitance shift due to th ...

Elsevier2009

New insights for using self-assembly materials to improve the detection stability in label-free DNA-chip and immuno-sensors

Bruno Samori, Luca Benini, Andrea Cavallini, Sandro Carrara, Anna Ferretti

This paper examines reliable advancements in low-cost DNA- and immuno-chips. Capacitance detection was successfully chosen to develop label-free bio-chips. Probe immobilization was rigorously investigated in order to obtain reliable capacitance measurement ...

Elsevier2009

Dynamical Spot Queries to Improve Specificity in P450s based Multi-Drugs Monitoring

Abhishek Garg, Giovanni De Micheli, Andrea Cavallini, Sandro Carrara

Personalized therapy requires accurate and frequent monitoring of drugs metabolic response in living organisms during drug treatments. In case of high risk side effects, e.g. therapies with interfering anti-cancer molecules cocktails, direct monitoring of ...

2009

Sensitivity Enhancement by Carbon Nanotubes: Applications to Stem Cell Cultures Monitoring

Giovanni De Micheli, Cristina Boero, Sandro Carrara

Nano-biosensing provides new tools to investigate cellular differentiation and proliferation. Upon the various metabolic compounds secreted by cells during life cycles, glucose, lactate and hydrogen peroxide (H2O2) are of first interest. Nanostructured ele ...

2009

Amperometric biosensor with nanostructured electrodes by using multi-alled carbon nanotubes for glucose detection in cell culture medium

Giovanni De Micheli, Cristina Boero, Sandro Carrara

The monitoring of metabolic compounds such as glucose is largely reported in literature. The applications of this type of analysis are mainly related to clinical purposes, e.g. in diabetes pathology, where a lot of studies are presented in literature. Rece ...

2009

3D Architecture and Replaceable Layers for Label-Free DNA Biochips

Yusuf Leblebici, Andrea Cavallini, Yüksel Temiz, Sandro Carrara

Recent advances in bio-sensing technologies have led to design of bio-sensor arrays for rapid identification and quantification of various biological agents such as drugs, gene expressions, proteins, cholesterol, fats, etc. Various dedicated sensing arrays ...

2009

Fabrication of Memristors with Poly-Crystalline Silicon Nanowires

Giovanni De Micheli, Sandro Carrara

Memristors are the two-terminal components that complete the symmetry between the fundamental circuit variables, and they are highly suitable for bioinspired and neuralnetwork-based computational systems due to their inherent memory effect. In this paper w ...

2009

Quantum Dots and Wires to improve Enzymes-Based Electrochemical Bio- sensing

Giovanni De Micheli, Cristina Boero, Sandro Carrara

An investigation on nano-structured electrodes to detect different metabolites is proposed in this paper. Three different metabolites are considered: glucose, lactate, and cholesterol. The direct detection of hydrogen peroxide is also considered since it d ...

2009

Nanoscale film structure related to capacitive effects in ethylene-glycol monolayers

Bruno Samori, Sandro Carrara

A large improvement of the electrochemical capacitive detection of ssDNA and antigens by using ethylene-glycol alkanethiol monolayers has been recently demonstrated. Alkanethiol monolayers without ethylene-glycol functionalization do not show the required ...

2009

Circuits Design and Nano-Structured Electrodes for Drugs Monitoring in Personalized Therapy

Giovanni De Micheli, Luca Benini, Andrea Cavallini, Sandro Carrara, Jacopo Olivo

Drug development and personalized therapy require accurate and frequent monitoring of the metabolic response by living tissues to treatments. In case of high risk side effects, e.g. therapies with interfering anti-cancer molecule cocktails, direct monitori ...

IEEE2008

Screen-printed electrodes based on carbon nanotubes and cytochrome P450scc for highly sensitive cholesterol biosensors

Bruno Samori, Sandro Carrara

This paper is concerned with an investigation of electron transfer between cytochrome P450scc (CYP11A1) immobilized on nanostructured rhodium-graphite electrodes. Multi-walled carbon nanotubes (MWCNT) were deposited onto the rhodium-graphite electrodes by ...

Elsevier2008

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