Ulrich Lorenz

Cette personne a quitté l’EPFL

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Publications associées (28)

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Visualizing Nanoscale Dynamics with Time-resolved Electron Microscopy

Marcel Drabbels, Ulrich Lorenz, Pavel Olshin

The large number of interactions in nanoscale systems leads to the emergence of complex behavior. Understanding such complexity requires atomic-resolution observations with a time resolution that is high enough to match the characteristic timescale of the ...

2022

Direct measurement of the critical cooling rate for the vitrification of water

Marcel Drabbels, Ulrich Lorenz, Constantin Richard Krüger, Nathan Junior Mowry

The vitrification of aqueous solutions through rapid cooling is a remarkable achievement that launched the field of cryo-electron microscopy (cryo-EM) and has enabled the cryopreservation of biological specimens. For judging the feasibility of a vitrificat ...

2025

Shaped Laser Pulses for Microsecond Time-Resolved Cryo-EM: Outrunning Crystallization during Flash Melting

Marcel Drabbels, Ulrich Lorenz, Constantin Richard Krüger, Nathan Junior Mowry

Water vitrifies if cooled at rates above 3 × 105 K/s. In contrast, when the resulting amorphous ice is flash heated, crystallization occurs even at a more than 10 times higher heating rate, as we have recently shown. This may present an issue for microseco ...

2024

Microsecond time-resolved cryo-electron microscopy

Ulrich Lorenz

Microsecond time-resolved cryo-electron microscopy has emerged as a novel approach for directly observing protein dynamics. By providing microsecond temporal and near-atomic spatial resolution, it has the potential to elucidate a wide range of dynamics tha ...

2024

Real-time observation of jumping and spinning nanodroplets

Marcel Drabbels, Ulrich Lorenz, Pavel Olshin, Jonathan Mark Voss

The manipulation of liquids at nanoscale dimensions is a central goal of the emergent nanofluidics field. Such endeavors extend to nanodroplets, which are ubiquitous objects involved in many technological applications. Here, we employ time-resolved electro ...

2020

Flash Melting Amorphous Ice

Marcel Drabbels, Ulrich Lorenz, Gabriele Bongiovanni, Constantin Richard Krüger, Nathan Junior Mowry

Water can be vitrified if it is cooled at high rates, which makes it possible to outrun crystallization in so-called no man’s land, a range of deeply supercooled temperatures where water crystallizes rapidly. Here, we study the reverse process in pure wate ...

2024

Sealed Samples for High-resolution, Microsecond Cryo-EM

Wyatt Abbott Curtis, Jakub Wenz, Marcel Drabbels, Ulrich Lorenz, Constantin Richard Krüger, Sarah Victoria Barrass

Oxford University Press (OUP)2025

A Planar Multipole Ion Trap/Time-of-Flight Mass Spectrometer

Thomas Rizzo, Ulrich Lorenz

We present a novel, hybrid ion trap/time-of-flight mass spectrometer that is based on a planar multipole design. Compared with Paul trap/time-of-flight instruments, this design possesses the principal advantages of higher injection efficiency and more homo ...

2011