Marc Moniatte

Cette personne a quitté l’EPFL

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Publications associées (29)

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Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA

Marc Moniatte, Romain Hamelin, Florence Armand

Plasmodium falciparum is the main cause of disease and death from malaria. P. falciparum virulence resides in the ability of infected erythrocytes (IEs) to sequester in various tissues through the interaction between members of the polymorphic P. falciparu ...

2019

Activation of a PAK-MEK signalling pathway in malaria parasite-infected erythrocytes

Romain Hamelin, Marc Moniatte

P>Merozoites of malaria parasites invade red blood cells (RBCs), where they multiply by schizogony, undergoing development through ring, trophozoite and schizont stages that are responsible for malaria pathogenesis. Here, we report that a protein kinase-me ...

Wiley-Blackwell2011

A mammalian transcription factor-specific peptide repository for targeted proteomics

Bart Deplancke, Marc Moniatte, Romain Hamelin, Jovan Simicevic

Site-specific transcription factors (TFs) play an essential role in mammalian development and function as they are vital for the majority of cellular processes. Despite their biological importance, TF proteomic data is scarce in the literature, likely due ...

Wiley-VCH GmbH2015

Surface charge of polymer coated SPIONs influences the serum protein adsorption, colloidal stability and subsequent cell interaction in vitro

Alke Fink, Marc Moniatte

It is known that the nanoparticle-cell interaction strongly depends on the physicochemical properties of the investigated particles. In addition, medium density and viscosity influence the colloidal behaviour of nanoparticles. Here, we show how nanoparticl ...

Royal Soc Chemistry2013

Superparamagnetic Nanoparticles as a Powerful Systems Biology. Characterization Tool in the Physiological Context

Jeffrey Alan Hubbell, Heinrich Hofmann, Alke Fink, Marc Moniatte, Benedikt Steitz, Andrija Finka

Recently, functionalized superparamagnetic iron oxide nanoparticles (SPIONs) have been utilized for protein separation and therapeutic delivery of DNA and drugs. The development of new methods and tools for the targeting and identification of specific biom ...

Wiley-Blackwell2008

Involvement of Plasmodium falciparum protein kinase CK2 in the chromatin assembly pathway

Marc Moniatte, Romain Hamelin, Guillem Dayer

Background: Protein kinase CK2 is a pleiotropic serine/threonine protein kinase with hundreds of reported substrates, and plays an important role in a number of cellular processes. The cellular functions of Plasmodium falciparum CK2 (PfCK2) are unknown. Th ...

2012

Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint

Davide Demurtas, Adrian Schmid, Cyntia De Piano, Marc Moniatte, Christophe Fuerer

Amyloid-beta (A beta) peptide oligomerization plays a central role in the pathogenesis of Alzheimer's disease (AD), and A beta oligomers are collectively considered an appealing therapeutic target for the treatment of AD. However, the molecular mechanisms ...

Elsevier Science Inc2016

Agents utiles dans le diagnostic et la thérapie de troubles liés à l'agrégation de bêta-amyloïde et procédés de criblage

Marc Moniatte

The present invention relates to novel fragments of beta-amyloid peptide and molecules binding thereto, as well as the use of said fragments and molecules in a method for prognosing/diagnosing and/or preventing/treating beta-amyloid aggregation related dis ...

2017

Phosphorylation Of The Var2Csa Extracellular Region Is Associated With Enhanced Adhesive Properties To The Placental Receptor Csa

Marc Moniatte, Romain Hamelin, Florence Armand

AMER SOC TROP MED & HYGIENE2019