Publications de Vladimir Mlynarik

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3'-deoxy-3'-[F-18]fluorothymidine ([F-18]FLT), a cell proliferation positron emission tomography (PET) tracer, has been shown in numerous tumors to be more specific than 2-deoxy-2-[F-18]fluoro-d-glucose ([F-18]FDG) but less sensitive. We studied the capaci ...

Tumor-initiating cells with stem cell properties are believed to sustain the growth of gliomas, but proposed markers such as CD133 cannot be used to identify these cells with sufficient specificity. We report an alternative isolation method purely based on ...

Ultra-short echo-time proton single voxel spectra of rat brain were obtained on a 14.1 T 26 cm horizontal bore system. At this field, the fitted linewidth in the brain tissue of adult rats was about 11 Hz. New, separated resonances ascribed to phosphocholi ...

After ischemic stroke, the ischemic damage to brain tissue evolves over time and with an uneven spatial distribution. Early irreversible changes occur in the ischemic core, whereas, in the penumbra, which receives more collateral blood flow, the damage is ...

Full signal intensity H-1-[C-13] NMR spectroscopy, combining a preceding C-13-editing block based on an inversion BISEP (B-1-insensitive spectral editing pulse) with a spin-echo coherence-based localization, was developed and implemented at 14.1 T. C-13 ed ...

Objectives: Sixty three healthy subjects were measured to assess dependence of brain metabolites on age using short- and long echo time spectroscopy in different brain regions. Material and methods: Younger and elderly humans were measured with long echo t ...

This study compares the performance and the reproducibility of quantitative T2, T2* and the magnetisation transfer ratio (MTR) of articular cartilage at 7T and 3T. ...

Background: Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. The impact of maternal supplementat ...

Reliable quantification of the macromolecule signals in short echo-time H-1 MRS spectra is particularly important at high magnetic fields for an accurate quantification of metabolite concentrations (the neurochemical profile) due to effectively increased s ...

Accurate assessment of the macromolecule contributions in short echo-time proton MRS spectra is important for a reliable quantification of the neurochemical profile. The aim of the present study was to assess two approaches based on using LCModel, which ta ...

Vladimir Mlynarik

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Increase of [F-18]FLT Tumor Uptake In Vivo Mediated by FdUrd: Toward Improving Cell Proliferation Positron Emission Tomography

RETRACTED: Marker-independent identification of glioma-initiating cells

H-1 NMR spectroscopy of rat brain in vivo at 14.1 Tesla: Improvements in quantification of the neurochemical profile

High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice

H-1-[C-13] NMR Spectroscopy of the Rat Brain During Infusion of [2-C-13] Acetate at 14.1 T

Metabolic changes in the normal ageing brain: Consistent findings from short and long echo time proton spectroscopy

Biochemical (T2, T2* and magnetisation transfer ratio) MRI of knee cartilage: feasibility at ultra-high field (7T) compared with high field (3T) strength

Definition and quantification of acute inflammatory white matter injury in the immature brain by MRI/MRS at high magnetic field

Quantification of in vivo short echo-time proton magnetic resonance spectra at 14.1 T using two different approaches of modelling the macromolecule spectrum

Comparison of two approaches to model the macromolecule spectrum for the quantification of short TE H-1 MRS spectra

Glutamine synthesis rate in the hyperammonaemic rat brain using simultaneous localized in vivo H-1 and N-15 MRS

Precision of metabolite concentrations obtained by LCModel as a function of the signal-to-noise ratio in rodent brain

Proton MRS investigation of human glioma models in nude mice at 14.1 T

Localized 1H[13C] NMR Measurement of N-acetyl-aspartate Turnover in Rat Brain

Proton T1 relaxation times of metabolites in human occipital white matter and grey matter at 7T

Diffusion MRI study of slowly growing human glioma models in mice at 14.1T

Abrogation of glutamate consumption in the central nervous system modifies brain metabolism and reshapes peripheral energy distribution

Proton and phosphorus MRS of a 5xFAD mouse model of Alzheimer's disease

High-Quality MR Spectroscopy of the Human Brain with Full Signal Intensity at Echo Times Below 6 ms on a Clinical Platform at 3T and 7T

Investigation of spatial distribution of metabolites in rat brain at elevated plasma glucose levels