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Ulrike Lehmann

Cette personne a quitté l’EPFL

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Publications associées (27)

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Two-dimensional magnetic manipulation of microdroplets on a chip as a platform for bioanalytical applications

Martinus Adela Maria Gijs, Virendra Kumar Parashar, Caroline Vandevyver, Ulrike Lehmann, Amar Rida

Manipulating biological samples in microliter droplets has vast potential in molecular diagnostics. We present a system for the two-dimensional (2D) magnetic manipulation of aqueous droplets suspended in silicone oil as a platform for on-chip bioanalysis. ...

Elsevier2006

Highly sensitive SnO2 sensor via reactive laser-induced transfer

Ulrike Lehmann

Gas sensors based on tin oxide (SnO2) and palladium doped SnO2 (Pd:SnO2) active materials are fabricated by a laser printing method, i.e. reactive laser-induced forward transfer (rLIFT). Thin films from tin based metal-complex precursors are prepared by sp ...

Nature Research2016

Microfluidic applications of magnetic particles for biological analysis and catalysis

Martinus Adela Maria Gijs, Ulrike Lehmann, Frédéric Lacharme

American Chemical Society2010

Two dimensional magnetic manipulation of microdroplets on a chip

Martinus Adela Maria Gijs, Virendra Kumar Parashar, Ulrike Lehmann, Amar Rida

In this paper we describe the two-dimensional (2D) magnetic manipulation of aqueous droplets suspended in silicone oil over the chip surface. The magnetic actuation is based on the force imposed on superparamagnetic microparticles inside the droplets. Thes ...

2005

Particle Shadow Tracking - Combining Magnetic Particle Manipulation with In-Situ Optical Detection in a CMOS Microsystem

Edoardo Charbon, Martinus Adela Maria Gijs, Cristiano Niclass, Ulrike Lehmann

We present a hybrid CMOS based microsystem where magnetic actuation of microparticles is combined with integrated optical detection via Single Photon Avalanche Diodes (SPADs). The system’s configuration permits the manipulation and detection of single magn ...

2007

Manipulation of magnetic microparticles in liquid phases for on-chip biomedical analysis methods

Ulrike Lehmann

Magnetic microparticles and their application in bioanalytical microfluidic systems have been steadily gaining interest in recent years. This progress is fueled by the comparatively large and long range magnetic forces that can be obtained independently of ...

EPFL2008

Monolithic Silicon Chip for Immunofluorescence Detection on Single Magnetic Beads

Edoardo Charbon, Martinus Adela Maria Gijs, Caroline Vandevyver, Ulrike Lehmann, Emile Dupont

While fluorescence detection is widely used for bioassays owing to its high sensitivity, a complete fluorescent microscopy setup, comprised of a light source, optical filters, a microscope body, and a camera, still is bulky equipment, compromising its use ...

2010

Fluorescent magnetic bead and cell differentiation/counting using a CMOS SPAD matrix

Edoardo Charbon, Martinus Adela Maria Gijs, Caroline Vandevyver, Ulrike Lehmann, Emile Dupont

We present a monolithic silicon chip comprising a matrix of 84 single photon avalanche diodes (SPADs) to detect and discriminate fluorescent beads or fluorescently labeled single cells in a polydimethyl(-siloxane) (PDMS) cartridge that is positioned on top ...

Elsevier2012

Two-Dimensional Magnetic Droplet Manipulation Platform for Miniaturized Bioanalytical Applications

Martinus Adela Maria Gijs, Virendra Kumar Parashar, Caroline Vandevyver, Ulrike Lehmann

We present a new approach for the manipulation of small liquid samples for the miniaturization of bioanalytical systems. In our system, minute liquid volumes are manipulated via the interaction of a changeable magnetic field and magnetic microparticles con ...

2007

Two dimensional magnetic manipulation of microdroplets on a chip

Martinus Adela Maria Gijs, Virendra Kumar Parashar, Ulrike Lehmann

2005

Microparticle photometry in a CMOS microsystem combining magnetic actuation and in-situ optical detection

Edoardo Charbon, Martinus Adela Maria Gijs, Cristiano Niclass, Ulrike Lehmann, Emile Dupont

We present a hybrid CMOS-based microfluidic system that combines magnetic actuation of microparticles with in situ optical detection using single photon avalanche diodes (SPADs). The decoupling of the principles used for actuation and sensing permits a hig ...

Elsevier2008

Particle-Shadow Tracking – Combining Magnetic Particle Manipulation with In-Situ Optical Detection in a CMOS Microsystem

Edoardo Charbon, Martinus Adela Maria Gijs, Cristiano Niclass, Ulrike Lehmann

2007

On-chip antibody handling and colorimetric detection in a magnetic droplet manipulation system

Martinus Adela Maria Gijs, Virendra Kumar Parashar, Caroline Vandevyver, Ulrike Lehmann

Miniaturized system for bioanalysis have been constantly gaining importance and interest within the recent years. The reduction of sample consumption and reaction time are some of the major advantages of such lab-on-a-chip applications. One of the greatest ...

2007

On-chip antibody handling and detection in a magnetic droplet manipulation system

Martinus Adela Maria Gijs, Virendra Kumar Parashar, Caroline Vandevyver, Ulrike Lehmann

2006

On-Chip Sandwich Immunoassay in an Integrated Magneto-Optical CMOS Microsystem

Edoardo Charbon, Martinus Adela Maria Gijs, Ulrike Lehmann, Emile Dupont

We report on an innovative approach to on-chip detection of single fluorescently-labeled magnetic micro-particles by means of Single Photon Avalanche Diode (SPAD) arrays. Our system enables particle separation through magnetic actuation and highly sensitiv ...

2008

A CMOS Microsystem Combining Magnetic Actuation and In-Situ Optical Detection of Microparticles

Edoardo Charbon, Martinus Adela Maria Gijs, Cristiano Niclass, Ulrike Lehmann

We present a CMOS-based hybrid microfluidic system that combines the manipulation of magnetic microparticles through a magnetic field with in situ optical detection via single photon avalanche diodes (SPADs). Magnetic particles are actuated within a glass ...

2007

Droplet-Based DNA Purification in a Magnetic Lab-on-a-Chip

Martinus Adela Maria Gijs, Virendra Kumar Parashar, Caroline Vandevyver, Ulrike Lehmann

Merge, Mix, Split and Transport, these are the main manipulation steps used for on-chip droplet-based DNA purification (see figure). The system is able to extract genomic material from dilute cell samples by using the actuation of magnetic microparticles w ...

Wiley-VCH Verlag GmbH2006

Ulrike Lehmann

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Two-dimensional magnetic manipulation of microdroplets on a chip as a platform for bioanalytical applications

Highly sensitive SnO2 sensor via reactive laser-induced transfer

Microfluidic applications of magnetic particles for biological analysis and catalysis

Two dimensional magnetic manipulation of microdroplets on a chip

Particle Shadow Tracking - Combining Magnetic Particle Manipulation with In-Situ Optical Detection in a CMOS Microsystem

Manipulation of magnetic microparticles in liquid phases for on-chip biomedical analysis methods

Monolithic Silicon Chip for Immunofluorescence Detection on Single Magnetic Beads

Fluorescent magnetic bead and cell differentiation/counting using a CMOS SPAD matrix

Two-Dimensional Magnetic Droplet Manipulation Platform for Miniaturized Bioanalytical Applications

Two dimensional magnetic manipulation of microdroplets on a chip

Microparticle photometry in a CMOS microsystem combining magnetic actuation and in-situ optical detection

Particle-Shadow Tracking – Combining Magnetic Particle Manipulation with In-Situ Optical Detection in a CMOS Microsystem

On-chip antibody handling and colorimetric detection in a magnetic droplet manipulation system

On-chip antibody handling and detection in a magnetic droplet manipulation system

On-Chip Sandwich Immunoassay in an Integrated Magneto-Optical CMOS Microsystem

A CMOS Microsystem Combining Magnetic Actuation and In-Situ Optical Detection of Microparticles

Droplet-Based DNA Purification in a Magnetic Lab-on-a-Chip

Droplets and DNA: Extracting and Purifying DNA in a Magnetic Droplet Manipulation System

Detection of Fluorescently Labelled Magnetic Particles for Lab-on-a-chip Applications

A Lab-on-a-Chip using magnetic droplets