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Bernard Lanz

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Publications associées (59)

Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopy

Yves Pilloud, Bernard Lanz, Rolf Gruetter, João Miguel das Neves Duarte, Cristina Ramona Cudalbu

Brain glutamine synthetase (GS) is an integral part of the glutamate-glutamine cycle and occurs in the glial compartment. In vivo Magnetic Resonance Spectroscopy (MRS) allows noninvasive measurements of the concentrations and synthesis rates of metabolites ...

Nature Publishing Group2012

Evaluation of glial metabolic fluxes in vivo with [2-13C] acetate infusion in mouse brain by 1H-[13C] NMR spectroscopy

Bernard Lanz, Rolf Gruetter, Lijing Xin, Hongxia Lei

2011

Impact of the prior knowledge on the quantification of in vivo 13C spectra using two different algorithms: LCModel and AMARES

Nicolas Kunz, Bernard Lanz, Rolf Gruetter, João Miguel das Neves Duarte, Cristina Ramona Cudalbu

2011

Compartmentalized Cerebral Metabolism of [1,6-(13)C]Glucose Determined by in vivo (13)C NMR Spectroscopy at 14.1 T

Bernard Lanz, Rolf Gruetter, João Miguel das Neves Duarte

Cerebral metabolism is compartmentalized between neurons and glia. Although glial glycolysis is thought to largely sustain the energetic requirements of neurotransmission while oxidative metabolism takes place mainly in neurons, this hypothesis is matter o ...

Frontiers Research Foundation2011

In Vivo Assessment of Neuronal Metabolic Fluxes in Mouse Brain by 1H-[13C] NMR Spectroscopy

Bernard Lanz, Rolf Gruetter, Lijing Xin, Hongxia Lei

2011

GLIAL GLYCOLYTIC GAPDH ACTIVITY MODULATES THE RESTING CEREBRAL METABOLIC RATE OF GLUCOSE AND CA+2- DEPENDENT EXCITATORY NEUROTRANSMITTER RELEASE

Giorgio Margaritondo, Bernard Lanz, Rolf Gruetter, Carole Poitry-Yamate, Laurent Lecomte

2011

Increase of [F-18]FLT Tumor Uptake In Vivo Mediated by FdUrd: Toward Improving Cell Proliferation Positron Emission Tomography

Bernard Lanz, Rolf Gruetter, David Viertl, Carole Poitry-Yamate, Hans-Anton Lehr

3'-deoxy-3'-[F-18]fluorothymidine ([F-18]FLT), a cell proliferation positron emission tomography (PET) tracer, has been shown in numerous tumors to be more specific than 2-deoxy-2-[F-18]fluoro-d-glucose ([F-18]FDG) but less sensitive. We studied the capaci ...

Elsevier2011

Imaging glutamine synthesis rates in the hyperammonemic rat brain

Bernard Lanz, Rolf Gruetter, Hanne Frenkel, Cristina Ramona Cudalbu

2010

In vivo simultaneous measurement of glutamine synthetase and glutamate dehydrogenase activity in the hyperammonemic rat brain using localized 1H and 15N MRS

Yves Pilloud, Bernard Lanz, Rolf Gruetter, Paul Romeo Vasos, Cristina Ramona Cudalbu

2010

In vivo Magnetic Resonance Spectroscopy (MRS) studies of brain metabolism during ammonia infusion

Bernard Lanz, Rolf Gruetter, Hanne Frenkel, Cristina Ramona Cudalbu

2010

H-1-[C-13] NMR Spectroscopy of the Rat Brain During Infusion of [2-C-13] Acetate at 14.1 T

Bernard Lanz, Rolf Gruetter, Lijing Xin

Full signal intensity H-1-[C-13] NMR spectroscopy, combining a preceding C-13-editing block based on an inversion BISEP (B-1-insensitive spectral editing pulse) with a spin-echo coherence-based localization, was developed and implemented at 14.1 T. C-13 ed ...

Wiley-Blackwell2010

Alteration of brain glycogen turnover in the awake rat

Pierre Magistretti, Bernard Lanz, Rolf Gruetter, Jean-Marie Petit, Hanne Frenkel

Nature Publishing Group2009

In vivo localized 15N and 1H MRS in the hyperammonaemic rat brain at 9.4T

Yves Pilloud, Bernard Lanz, Rolf Gruetter, Cristina Ramona Cudalbu

2009

BISEP-based, Ultra-short TE 1H–[13C] NMR Spectroscopy of the Rat Brain at 14.1 T

Bernard Lanz, Rolf Gruetter, Lijing Xin, Hanne Frenkel

2009

Simultaneous Localized in vivo 1H and 15N MRS of Glutamine Synthesis in the hyperammonaemic rat brain

Yves Pilloud, Bernard Lanz, Rolf Gruetter, Cristina Ramona Cudalbu

2009

Measurements of glial metabolic fluxes with C-11-acetate using positron emission and an adapted NMR-based metabolic modeling approach

Bernard Lanz, Rolf Gruetter

Nature Publishing Group2009

MEASUREMENT OF GLUTAMINE SYNTHESIS RATE IN THE HYPERAMMONAEMIC RAT BRAIN USING IN VIVO 1H AND 15N MRS

Bernard Lanz, Rolf Gruetter, Cristina Ramona Cudalbu

2009

Glutamine synthesis rate in the hyperammonaemic rat brain using simultaneous localized in vivo H-1 and N-15 MRS

Yves Pilloud, Bernard Lanz, Rolf Gruetter, Cristina Ramona Cudalbu

Nature Publishing Group2009

Alteration of brain glycogen turnover in the conscious rat after 5h of prolonged wakefulness

Pierre Magistretti, Bernard Lanz, Rolf Gruetter, Jean-Marie Petit, Hanne Frenkel

Although glycogen (Glyc) is the main carbohydrate storage component, the role of Glyc in the brain during prolonged wakefulness is not clear. The aim of this study was to determine brain Glyc concentration ([]) and turnover time (tau) in euglycemic conscio ...

Elsevier2009

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