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Maria Carola Colombo

Cette personne a quitté l’EPFL

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Publications associées (5)

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On the structural stability of the free and metal-loaded c-terminal domain of the prion protein

Maria Carola Colombo

A misfolded conformer of the cellular prion protein, denoted as scrapie prion protein, is considered responsible for a variety of fatal neurodegenerative diseases. Both, the function of the protein in its native conformation as well as the factors that tri ...

EPFL2006

Enhanced Sampling Molecular Dynamics Identifies PrPSc Structures Harboring a C-Terminal beta-Core

Ursula Röthlisberger, Ivano Tavernelli, Maria Carola Colombo

We perform a replica exchange molecular dynamics simulation corresponding to a 2.8 mu s total time for the extensive enhanced sampling of the conformational space of the C-terminal part (residues 124-226) of the mouse prion protein (PrP); 1.3% of the confo ...

Amer Chemical Soc2012

Hybrid QM/MM molecular dynamics study of copper binding sites in the C-terminal domain of mouse prion protein

Ursula Röthlisberger, Leonardo Guidoni, Maria Carola Colombo

2008

Estimate on the Dimension of the Singular Set of the Supercritical Surface Quasigeostrophic Equation

Maria Carola Colombo, Silja Noëmi Aline Haffter

We consider the SQG equation with dissipation given by a fractional Laplacian of order α

2021

Continuity Of Multimarginal Optimal Transport With Repulsive Cost

Maria Colombo, Maria Carola Colombo, Federico Stra

We provide sharp conditions for the finiteness and the continuity of multimarginal optimal transport with repulsive cost, expressed in terms of a suitable concentration property of the measure. To achieve this result, we analyze the Kantorovich potentials ...

2019