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Jérémy Bérard

Cette personne a quitté l’EPFL

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Publications associées (4)

Page 1 sur 1

Nouvelles approches synthétiques de prodrogues de cyclosporine A et d'analogues antiviraux

Jérémy Bérard

The cyclosporins comprise a family of cyclic 11-peptides containing seven N-methylated, hydrophobic amino acids. Cyclosporine A (CsA) representing the major member of this family is widely used as immunosuppressive agent in organ transplantations. The biol ...

EPFL2008

Switch-peptides as folding precursors in self-assembling peptides and amyloid fibrillogenesis

Hilal Lashuel, Richard Alan Mimna, Karine Murat, Adrian Schmid, Marie-Stéphanie Camus, Jérémy Bérard

The study of conformational transitions of peptides has obtained considerable attention recently because of their importance as a mol. key event in a variety of degenerative diseases. However, the study of peptide self-assembly into beta-sheets and amyloid ...

2007

Switch-peptides: from conformational studies to Alzheimer's disease

Hilal Lashuel, Richard Alan Mimna, Lydiane Jeanine Saucède, Karine Murat, Marie-Stéphanie Camus, Sonia Dos Santos, Jérémy Bérard

A review. Studies on designed peptides that exhibit high tendencies for medium-induced conformational transitions have recently attracted much attention because structural changes are considered as mol. key processes in degenerative diseases. The exptl. ac ...

2006

Switch-peptides as folding precursors in amyloid fibrillogenesis

Richard Alan Mimna, Lydiane Jeanine Saucède, Karine Murat, Marie-Stéphanie Camus, Sonia Dos Santos, Jérémy Bérard

Intramol. O,N-acyl migration reactions were used as structural switch (S-elements) from a depsipeptide bond contg., unfolded state (Soff) to an all-amide, native states (Son). Chem. or enzymically triggered acyl migrations allowed for the controlled induct ...

2006