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Sandrine Gerber

Cette personne a quitté l’EPFL

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Publications associées (97)

Page 4 sur 5

Spongistatins : biological activity and synthetic studies

Pierre Vogel, Sandrine Gerber

During the last two decades, marine organisms such as sponges, tunicates, softcoral and starfish proved to be productive sources of structurally complex metabolites presenting unprecedented architectures.[1] These marine natural products often display unex ...

2008

Simultaneous Multi-Harmonic Imaging of Nanoparticles in Tissues for Increased Selectivity

Sandrine Gerber, Luigi Bonacina, Solène Marcelle Françoise Marie Passemard, Davide Städler, Sébastien Courvoisier

We investigate the use of Bismuth Ferrite (BFO) nanoparticles for tumor tissue labelling in combination with infrared multi-photon excitation at 1250 nm. We report the efficient and simultaneous generation of second and third harmonic by the nanoparticles. ...

Amer Chemical Soc2015

Combination of neonatal porcine islets with mesenchymal stem cells of human and porcine origin improves islet function

Sandrine Gerber, Luca Szabó

WILEY2019

Laureates: Junior Prizes of the SCS Fall Meeting 2015

Sandrine Gerber

Swiss Chemical Soc2016

Fractional Spin-Labeling of Polymers for Enhancing NMR Sensitivity by Solvent-Free Dynamic Nuclear Polarization

Geoffrey Bodenhausen, Sandrine Gerber, Andrzej Sienkiewicz, Sami Jannin, Pascal Miéville, Françoise Borcard, Marc Anthony Caporini

Wiley-Blackwell2011

Synthetic studies toward the CD spiroketal of spongistatins

Pierre Vogel, Sandrine Gerber, Sylvain Favre

Starting from the readily available meso-methylenedi(8-oxa-3-oxobicyclo[3.2.1]hept-6-en-1-yl) (1), meso-1,1'-methylidene [(4R,4'S,6R,6'S)-4,6-dioxycyclohept-1-en-1-yl]tetrasilylethers (7, 8) were obtained and transformed into all-syn 1,3,5,11,13,15-hexahyd ...

Wiley-Blackwell2010

Convenient synthesis of heterobifunctional poly(ethylene glycol) suitable for the functionalization of iron oxide nanoparticles for biomedical applications

Sandrine Gerber, Luigi Bonacina, Solène Marcelle Françoise Marie Passemard, Davide Städler, Phally Kong

A straightforward route is proposed for the multi-gram scale synthesis of heterobifunctional poly(ethylene glycol) (PEG) oligomers containing combination of triethyloxysilane extremity for surface modification of metal oxides and amino or azido active end ...

Elsevier2013

Cross-Reactive Alginate Derivatives for the Production of Dual Ionic−Covalent Hydrogel Microspheres Presenting Tunable Properties for Cell Microencapsulation

Sandrine Gerber, Aurélien Bornet, François Rémi Pierre Noverraz, Luca Szabó

The production of hydrogel micropsheres (MS) presenting physical, mechanical, and biological properties which can be modulated by their chemical composition is required to enlarge the panel of biomaterials for cell transplantation therapies. Functionalizat ...

2019

Strategies to Functionalize the Anionic Biopolymer Na-Alginate Without Restricting its Polyelectrolyte Properties

Sandrine Gerber, Jutta Christine Wandrey, Luca Szabó

The natural anionic polyelectrolyte alginate and its derivatives are of particular interest for pharmaceutical and biomedical applications. Most interesting for such applications are alginate hydrogels, which can be processed into various shapes, self-stan ...

2020

Combination of neonatal porcine islets with mesenchymal stem cells of human and porcine origin improves islet function

Sandrine Gerber, Luca Szabó

WILEY2019

Recent Advances in Alginate-Based Hydrogels for Cell Transplantation Applications

Sandrine Gerber, François Rémi Pierre Noverraz, Alireza Kavand

With its exceptional biocompatibility, alginate emerged as a highly promising biomaterial for a large range of applications in regenerative medicine. Whether in the form of microparticles, injectable hydrogels, rigid scaffolds, or bioinks, alginate provide ...

2024

Surface Functionalisation of Alumina Ceramic Foams with Organic Ligands

Sandrine Gerber, Vincent Laporte, Pascal Miéville, Françoise Borcard, Marc Anthony Caporini

Different anchoring groups have been studied with the aim of covalently binding organic linkers to the surface of alumina ceramic foams. The results suggested that a higher degree of functionalisation was achieved with a pyrogallol derivative - as compared ...

2012

Surface Functionalization of Nanocarriers with Anti-EGFR Ligands for Cancer Active Targeting

Alessandra Spada, Sandrine Gerber

Active cancer targeting consists of the selective recognition of overexpressed biomarkers on cancer cell surfaces or within the tumor microenvironment, enabled by ligands conjugated to drug carriers. Nanoparticle (NP)-based systems are highly relevant for ...

MDPI2025

Human Mesenchymal Stromal Cells Improve Survival And Function Of Pancreatic Islets By Cell-To-Cell Contact

Sandrine Gerber, Jutta Christine Wandrey, Redouan Mahou, Solène Marcelle Françoise Marie Passemard

Wiley-Blackwell2015

Human mesenchymal stem cells for the treatment of steatohepatitis

Sandrine Gerber

LIPPINCOTT WILLIAMS & WILKINS2019

Beneficial effects of human mesenchymal stromal cells on porcine hepatocytes viability and albumin secretion

Sandrine Gerber, Solène Marcelle Françoise Marie Passemard

Wiley2017

Studies toward new anti-cancer strategies based on alpha-mannosidase inhibition

Sandrine Gerber

Changes in the glycosylation pattern of cellular glycoproteins constitute a hallmark in human cancer and influence tumour progression, suggesting that inhibitors of selected glycosidases may control cancer invasion. Following the studies on swainsonine, a ...

Schweizerische Chemische Gesellschaft2010

Pyrrolidine derivatives as new inhibitors of alpha-mannosidases and growth inhibitors of human cancer cells

Pierre Vogel, Sandrine Gerber, Hélène Fiaux

New pyrrolidine-3,4-diol derivatives were prepared from D-(-)- and L(+)-phenylglycinol and tested for their ability to inhibit 25 commercial glycosidases. The influence of the substitution of the lateral side chain and of the pyrrolidine ring on the enzyme ...

2006

Noniterative approach to the total asymmetric synthesis of 15-carbon polyketides and analogs with high stereodiversity

Pierre Vogel, Sandrine Gerber, Marc-Etienne Schwenter, Kai Torsten Meilert

Starting from inexpensive furan and furfuryl alcohol, a noniterative approach to the synthesis of pentadeca-1,3,5,7,9,11,13,15-octols and their derivatives has been developed. The method relies upon the double [4+3]-cycloaddition of 1,1,3-trichloro-2-oxyla ...

2005

Synthesis and Biological Evaluation of Modified 2-Deoxystreptamine Dimers

Sandrine Gerber, Gérald Coste

Aminoglycosides are powerful antibiotics, but the emergence of resistant bacterial strains has prompted the search for analogues with better pharmacological profiles. The synthesis of 2-deoxystreptamine (2-DOS) dimers linked by polyamines and analogues bas ...

2011