Pressure pulse injection is proposed as an alternative technique to electrokinetic injection for use in continuous sample flow electrophoresis microchips. During chip operation, sample and buffer solutions are electrokinetically driven near to the entrance ...

2006

A Lab-on-a-Chip using magnetic droplets

Martinus Gijs, Caroline Vandevyver, Virendra Kumar Parashar, Ulrike Lehmann

2006

Microfluidic system for analytical applications : a magnetic droplet-based Lab-on-a-Chip

Martinus Gijs, Caroline Vandevyver, Virendra Kumar Parashar, Ulrike Lehmann

2006

DNA capture and elution in a magnetic droplet manipulation system

Martinus Gijs, Caroline Vandevyver, Virendra Kumar Parashar, Ulrike Lehmann

2006

Single potential electrophoresis microchip with reduced bias using pressure pulse injection

Martinus Gijs, Frédéric Lacharme

2006

Chip-based non-invasive voltage clamp on Xenopus laevis oocytes

Thomas Lehnert, Martinus Gijs, Elodie Deborah Dahan

2006

Cell sealing on glass-coated micro- and nano-apertures

Thomas Lehnert, Martinus Gijs, Yves Moser

2006

Droplets and DNA: Extracting and Purifying DNA in a Magnetic Droplet Manipulation System

Martinus Gijs, Caroline Vandevyver, Virendra Kumar Parashar, Ulrike Lehmann

2006

DNA biosensor using fluorescence microscopy and impedance spectroscopy

Martinus Gijs, Daniel Berdat

Two types of DNA biosensors are presented. Both sensing principles are demonstrated using synthetic oligomer single-stranded DNA (ssDNA) with concentrations in the micromolar range. A first sensor type is based on the detection of fluorescently labeled ssD ...

2006

Fabrication and characterization of three-dimensional micro-lens arrays in sol-gel glass

Abdeljalil Sayah, Martinus Gijs, Virendra Kumar Parashar, Jean-Baptiste Robert Orhan

Institute of Electrical and Electronics Engineers2006

Microfluidic integration of gel-based reference electrodes for electrophysiological measurements on chip

Thomas Lehnert, Martinus Gijs, Elodie Deborah Dahan

2006

On-chip antibody handling and detection in a magnetic droplet manipulation system

Martinus Gijs, Caroline Vandevyver, Virendra Kumar Parashar, Ulrike Lehmann

2006

Two-dimensional magnetic manipulation of microdroplets on a chip as a platform for bioanalytical applications

Martinus Gijs, Amar Rida, Caroline Vandevyver, Virendra Kumar Parashar, Ulrike Lehmann

Manipulating biological samples in microliter droplets has vast potential in molecular diagnostics. We present a system for the two-dimensional (2D) magnetic manipulation of aqueous droplets suspended in silicone oil as a platform for on-chip bioanalysis. ...

2006

Magnetic on-chip DNA Extraction in a Droplet-Based Microsystem

Martinus Gijs, Caroline Vandevyver, Virendra Kumar Parashar, Ulrike Lehmann

2006

Droplet-Based DNA Purification in a Magnetic Lab-on-a-Chip

Martinus Gijs, Caroline Vandevyver, Virendra Kumar Parashar, Ulrike Lehmann

Merge, Mix, Split and Transport, these are the main manipulation steps used for on-chip droplet-based DNA purification (see figure). The system is able to extract genomic material from dilute cell samples by using the actuation of magnetic microparticles w ...

Wiley-VCH Verlag GmbH2006

Defect structure in micropillars using X-ray microdiffraction

Thomas Lehnert, Martinus Gijs, Helena Van Swygenhoven, Steven Van Petegem

AIP American Institute of Physics2006

Pumping of mammalian cells with a nozzle-diffuser micropump

Christophe Yamahata, Horst Vogel, Martinus Gijs, Caroline Vandevyver, Paulina Izewska, Frédéric Lacharme

We discuss the successful transport of jurkat cells and 5D10 hybridoma cells using a reciprocating micropump with nozzle-diffuser elements. The effect of the pumping action on cell viability and proliferation, as well as on the damaging of cellular membran ...

Royal Society of Chemistry2005

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