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Philippe Pittet

Cette personne a quitté l’EPFL

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Publications associées (5)

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SciFi detector and associated method for real-time determination of profile and output factor for small fields in stereotactic radiotherapy

Guido Haefeli, Frédéric Blanc, Plamen Hristov Hopchev, Philippe Pittet

Purpose For determining small-field profile and output factor during stereotactic radiotherapy quality assurance (QA) procedures, we propose a novel system based on the scintillating fiber (SciFi) detector with output image acquisition and processing to al ...

WILEY2020

Evidence for signaling via gap junctions from smooth muscle to endothelial cells in rat mesenteric arteries: possible implication of a second messenger

Jean-Jacques Meister, Jean-Louis Bény, Michèle Koenigsberger, Philippe Pittet, Mathieu Lamboley

We investigated heterocellular communication in rat mesenteric arterial strips at the cellular level using confocal microscopy. To visualize Ca(2+) changes in different cell populations, smooth muscle cells (SMCs) were loaded with Fluo-4 and endothelial ce ...

Elsevier2005

Cadherins establish mechano-resistant junctions between fibrogenic fibroblasts

Philippe Pittet

During wound healing and in a variety of fibrocontractive diseases, fibroblasts differentiate into contractile myofibroblasts by acquiring stress fibers and by expressing α-smooth muscle actin (α-SMA). Myofibroblasts of wound granulation tissue, in contras ...

EPFL2008

Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds

Andrzej Kulik, Boris Hinz, Jean-Jacques Meister, Kyumin Lee, Philippe Pittet

We have previously shown that the switch from N-cadherin to OB-cadherin expression increases intercellular adhesion between fibroblasts during their transition from a migratory to a fibrogenic phenotype. Using atomic force microscopy we here show that part ...

2008

Ob-cadherin establishes mechano-resistant junctions between myofibroblasts

Andrzej Kulik, Boris Hinz, Jean-Jacques Meister, Kyumin Lee, Philippe Pittet

2007