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BIO-221: Cell and developmental biology for engineers

Résumé

Students will learn essentials of cell and developmental biology with an engineering mind set, with an emphasis on animal systems and quantitative approaches.

Séances de cours

Enseignant·e

Andrew Charles Oates

After an undergraduate degree in Biochemistry at the University of Adelaide with Honours in Robert Saint’s lab, Andrew Oates received his Ph.D. at the Ludwig Institute for Cancer Research and the University of Melbourne in the lab of Andrew Wilks. His postdoctoral time was at Princeton University and the University of Chicago in the lab of Robert Ho, where his studies on the segmentation clock in zebrafish began in 1998. In 2003 he moved to Germany and started his group at the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden. In 2012 he accepted a position at University College London as Professor of vertebrate developmental genetics and moved his group to the MRC-National Institute for Medical Research at Mill Hill in London. From April 2015, he became a member of the Francis Crick Institute in London. In September 2016, he joined École polytechnique fédéral de Lausanne (EPFL) in Switzerland as a Professor, where he is the head of the Timing, Oscillation, Patterns Laboratory. From April 2018 he served as Director of the Institute of Bioengineering, and from January 2021 became the Dean of the School of Life Sciences. The Timing, Oscillation, Patterns Laboratory is composed of biologists, engineers, and physicists using molecular genetics, quantitative imaging, and theoretical analysis to study a population of coupled genetic oscillators in the vertebrate embryo termed the segmentation clock. This system drives the rhythmic, sequential, and precise formation of embryonic body segments, exhibiting rich spatial and temporal phenomena spanning from molecular to tissue scales.

Source officielle

Page Moodle

http://go.epfl.ch/BIO-221

Résumé

Students will learn essentials of cell and developmental biology with an engineering mind set, with an emphasis on animal systems and quantitative approaches.

Séances de cours

Enseignant·e

Andrew Charles Oates

Source officielle

Page Moodle

http://go.epfl.ch/BIO-221

Séances de ce cours (32)

Motif à grain fin : inhibition latérale

Explore le développement de la vulve chez C. elegans et les voies de signalisation complexes impliquées dans l'induction et l'inhibition de l'expression des gènes.

Microscopie Super Résolution: Techniques et Applications

Explore l'histoire et les progrès des techniques de microscopie, y compris l'imagerie en super résolution avec les microscopes conventionnels.

Systèmes modèles en biologie centriole

Explore les questions fondamentales et les systèmes modèles en biologie centriole, en abordant la division cellulaire asymétrique et les aspects pertinents de la santé humaine.

Phénotypes de cellules souches et analyse de la lignée

Discute des phénotypes LGR5 chez la souris et des techniques d'analyse de lignée.

Mort cellulaire programmée : mécanismes et implications

Explore les mécanismes de mort cellulaire programmée, y compris l'apoptose et l'autophagie, en mettant l'accent sur leurs implications dans divers organismes et processus de régénération.

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