Concept

Cognitive impairment

Publications associées (28)

Robot-induced hallucinations in Parkinson’s disease depend on altered sensorimotor processing in fronto-temporal network

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Nathan Quentin Faivre, Giulio Rognini, Fosco Bernasconi, Michela Bassolino, Jevita Potheegadoo, Michel Akselrod, Eva Blondiaux, Giedre Stripeikyte, Matteo Franza

Hallucinations in Parkinson’s disease (PD) are disturbing and frequent non-motor symptoms and constitute a major risk factor for psychosis and dementia. We report a robotics-based approach applying conflicting sensorimotor stimulation, enabling the inducti ...

2021

Late Fusion of the Available Lexicon and Raw Waveform-based Acoustic Modeling for Depression and Dementia Recognition

Petr Motlicek, Mathew Magimai Doss, Subrahmanya Pavankumar Dubagunta, Julian David Fritsch

Mental disorders, e.g. depression and dementia, are categorized as priority conditions according to the World Health Organization (WHO). When diagnosing, psychologists employ structured questionnaires/interviews, and different cognitive tests. Although acc ...

ISCA-INT SPEECH COMMUNICATION ASSOC2021

Dysmaturation Observed as Altered Hippocampal Functional Connectivity at Rest Is Associated With the Emergence of Positive Psychotic Symptoms in Patients With 22q11 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Maude Schneider, Daniela Maria Zöller, Farnaz Delavari

BACKGROUND: Hippocampal alterations are among the most replicated neuroimaging findings across the psychosis spectrum. Moreover, there is strong translational evidence that preserving the maturation of hippocampal networks in mice models prevents the progr ...

ELSEVIER SCIENCE INC2021

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer's disease

Christopher Clark

Background Multiple pathophysiological processes have been described in Alzheimer's disease (AD). Their inter-individual variations, complex interrelations, and relevance for clinical manifestation and disease progression remain poorly understood. We hypot ...

2021

Clinical connectome fingerprints of cognitive decline

Enrico Amico

Brain connectome fingerprinting is rapidly rising as a novel influential field in brain network analysis. Yet, it is still unclear whether connectivity fingerprints could be effectively used for mapping and predicting disease progression from human brain d ...

2021

Impaired cognitive flexibility and heightened urgency are associated with increased alcohol consumption in rodent models of excessive drinking

Emanuela De Falco

Alcohol use disorder (AUD) is characterized by impairments in decision-making that can exist as stable traits or transient states. Cognitive inflexibility reflects an inability to update information that guides decision-making and is thought to contribute ...

WILEY2021

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments

Graham Knott, Nicole Déglon, Corrado Cali

Astrocytes orchestrate neural development by powerfully coordinating synapse formation and function and, as such, may be critically involved in the pathogenesis of neurodevelopmental abnormalities and cognitive deficits commonly observed in psychiatric dis ...

2020

Agito ergo sum: Correlates of spatio-temporal motion characteristics during fMRI

Dimitri Nestor Alice Van De Ville, Thomas William Arthur Bolton

The impact of in-scanner motion on functional magnetic resonance imaging (fMRI) data has a notorious reputation in the neuroimaging community. State-of-the-art guidelines advise to scrub out excessively corrupted frames as assessed by a composite framewise ...

2020