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Concept

Anesthésie péridurale

Publications associées (10)

Bistable Puncturing Tool for Retinal Vein Cannulation

Simon Nessim Henein, Yves Bellouard, Charles Baur, Lisa Anaïs Jeanne Bonnefoy

An innovative surgical tool prototype dedicated to safe puncturing has been developed for the treatment of retinal vein occlusions (RVOs). The tool is manufactured monolithically by femtolaser printing in fused silica. It consists of a programmable bistabl ...

2020

Automatic clustering of spinal reflexes evoked by epidural electrical stimulation of the cervical spinal cord in non-human primates

Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Jocelyne Bloch, Giuseppe Schiavone, Katie Zhi Zhuang

Epidural electrical stimulation of the spinal cord elicits motor responses by recruiting large sensory afferents in the posterior roots. Divergence of excitatory inputs provided by these fibers generates a variety of shapes, latencies and amplitudes in the ...

2019

Long-term functionality of a soft electrode array for epidural spinal cord stimulation in a minipig model

Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Marco Capogrosso, Giuseppe Schiavone, Florian Dylan Fallegger, Nicolas Vachicouras, Fabien Bertrand Paul Wagner, Xiaoyang Kang

Long-term biointegration of man-made neural interfaces is influenced by the mechanical properties of the implant materials. Substantial experimental work currently aims at replacing conventional hard implant materials with soft alternatives that can favour ...

IEEE2018

Advantages of soft subdural implants for the delivery of electrochemical neuromodulation therapies to the spinal cord

Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Pavel Musienko, Eduardo Martin Moraud, Ivan Rusev Minev, Nikolaus Wenger, Jérôme Gandar, Nathan Antoine Greiner

Objective. We recently developed soft neural interfaces enabling the delivery of electrical and chemical stimulation to the spinal cord. These stimulations restored locomotion in animal models of paralysis. Soft interfaces can be placed either below or abo ...

2018

Neuromodulation in the restoration of function after spinal cord injury

Nicholas David James

Neuromodulation, the use of electrical interfaces to alter neuronal activity, has been successful as a treatment approach in several neurological disorders, including deep brain stimulation for Parkinson's disease and epidural spinal stimulation for chroni ...

2018

Virtual reality improves embodiment and neuropathic pain caused by spinal cord injury

Olaf Blanke, Marco Solcà, Roberta Ronchi, Estelle Palluel, Polona Pozeg

Objective: To investigate changes in body ownership and chronic neuropathic pain in patients with spinal cord injury (SCI) using multisensory own body illusions and virtual reality (VR). Methods: Twenty patients with SCI with paraplegia and 20 healthy cont ...

Lippincott Williams & Wilkins2017

Sepiapterin reductase inhibitors

Kai Johnsson, Katarzyna Irena Gorska

Inhibitors of sepiapterin reductase and uses of sepiapterin reductase inhibitors in analgesia, treatment of acute and chronic pain, anti-inflammation, and immune cell regulation are disclosed. ...

2017

A real-time platform for studying the modulatory capacity of epidural stimulation after spinal cord injury

Silvestro Micera, Grégoire Courtine, Eduardo Martin Moraud, Jérôme Gandar, Nikolaus Wenger, Pavel Musienko

Epidural electrical stimulation (EES) showed promises to improve standing and walking after neurological disorders. To date, EES has been delivered continuously, although time-dependent stimulations would likely be more efficient to activate specific subse ...

Ieee2013

Spinal and Supraspinal Control of the Direction of Stepping during Locomotion

Pavel Musienko

Most bipeds and quadrupeds, in addition to forward walking, are also capable of backward and sideward walking. The direction of walking is determined by the direction of stepping movements of individual limbs in relation to the front-to-rear body axis. Our ...

Society for Neuroscience2012

Plasticity of functional connectivity in the adult spinal cord

Grégoire Courtine

This paper emphasizes several characteristics of the neural control of locomotion that provide opportunities for developing strategies to maximize the recovery of postural and locomotor functions after a spinal cord injury (SCI). The major points of this p ...

2006