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Concept

Phage T4

Publications associées (24)

Structure and Biophysical Properties of a Triple-Stranded Beta-Helix Comprising the Central Spike of Bacteriophage T4

Laure Menin, Petr Leiman, Sergii Buth

Gene product 5 (gp5) of bacteriophage T4 is a spike-shaped protein that functions to disrupt the membrane of the target cell during phage infection. Its C-terminal domain is a long and slender -helix that is formed by three polypeptide chains wrapped aroun ...

Mdpi Ag2015

Listeria phage A511, a model for the contractile tail machineries of SPO1-related bacteriophages

Petr Leiman, Mikhail Shneyder

Recognition of the bacterial host and attachment to its surface are two critical steps in phage infection. Here we report the identification of Gp108 as the host receptor-binding protein of the broad host-range, virulent Listeria phage A511. The ligands fo ...

Wiley-Blackwell2014

Elucidating bacterial regrowth: Effect of disinfection conditions in dark storage of solar treated secondary effluent

César Pulgarin, Stefanos Giannakis

In this study, we systematically investigate solar disinfection of synthetic secondary wastewater, with the effort to decrypt the effects disinfection conditions have on post-irradiation bacterial regrowth in the dark. A full factorial design of 240 experi ...

Elsevier2014

Phage Selection of Photoswitchable Peptide Ligands

Christian Heinis, Shiyu Chen, Inmaculada Rentero Rebollo, Silvia Bellotto

Photoswitchable ligands are powerful tools to control biological processes at high spatial and temporal resolution. Unfortunately, such ligands exist only for a limited number of proteins and their development by rational design is not trivial. We have dev ...

2014