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Concept

Hypertrophie bénigne de la prostate

Publications associées (29)

Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence

Patrick Fraering, Mitko Dimitrov, Hermeto Gerber

Activation of NOTCH signalling is associated with advanced prostate cancer and treatment resistance in prostate cancer patients. However, the mechanism that drives NOTCH activation in prostate cancer remains still elusive. Moreover, preclinical evidence of ...

Nature Publishing Group2016

Label-Free Ultrasensitive Memristive Aptasensor

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki

We present the very first worldwide ever-reported electrochemical biosensor based on a memristive effect and DNA aptamers. This novel device is developed to propose a completely new approach in cancer diagnostics. In this study, an affinity-based technique ...

American Chemical Society2016

Study on the bio-functionalization of memristive nanowires for optimum memristive biosensors

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Ioulia Tzouvadaki

Semiconductor nanowires are emerging as promising building blocks for biosensors enabling direct electrical detection of various biomolecules. In this framework, two-terminal Schottky-barrier silicon (Si) nanowire arrays that exhibit memristive electrical ...

Royal Society of Chemistry2016

Interobserver variability study for daily cone beam computed tomography registration of prostate volumetric modulated arc therapy

Purpose. - This work evaluated the interobserver variability in cone beam computed tomography (CBCT) registration for prostate cancers treated with intensity-modulated radiotherapy. Material and methods. - Twelve technologists realized 286 CBCT/CT registra ...

Elsevier2015

Memristive Biosensors for PSA-IgM Detection

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki

Prostate cancer is the most common cancer among men except for skin cancer, and the detection at early stages is crucial. In the present work, nanofabricated memristive biosensors are subjected to surface bio-modification targeting at prostate-specific ant ...

2015

Bio-functionalization study of Memristive- Biosensors for Early Detection of Prostate Cancer

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki

Silicon nanowires are reported for their application in bio sensing area and their potential in the detection of various biomolecules. In the present work, freestanding two-terminal Schottky-barrier silicon nanowire arrays exhibiting memristive behavior ar ...

2015

LSPR Chip for Parallel, Rapid, and Sensitive Detection of Cancer Markers in Serum

Sebastian Maerkl

Label-free biosensing based on metallic nano-particles supporting localized surface plasmon resonances (LSPR) has recently received growing interest (Anker, J. N., et al. Nat. Mater. 2008, 7, 442-453). Besides its competitive sensitivity (Yonzon, C. R., et ...

Amer Chemical Soc2014

Is There a Need for Smooth Muscle Cell Transplantation in Urethral Reconstruction?

Peter Frey

Background: Hypospadias and urethral strictures are conditions requiring additional tissue for reconstruction. Due to a limited source of tissue, autologous skin and oral mucosa are frequently used. However, long-term follow-up studies demonstrated signifi ...

Mary Ann Liebert, Inc2014

A 1024-sample serum analyzer chip for cancer diagnostics

Sebastian Maerkl

We present a platform that combines microarrays and microfluidic techniques to measure four protein biomarkers in 1024 serum samples for a total of 4096 assays per device. Detection is based on a surface fluorescence sandwich immunoassay with a limit of de ...

Royal Society of Chemistry2014