Décussation

Accelerated Microstructure Imaging via Convex Optimization (AMICO) in crossing fibers

Jean-Philippe Thiran, Alessandro Daducci, Yves Wiaux, Erick Jorge Canales Rodriguez, Anna Auria Rasclosa

Mapping the local microstructure properties of the tissue in the brain is crucial to understand any pathological condition from a biological perspective. In recent years, microstructure-imaging techniques aimed at extracting such precious information by us ...

2015

Characterizing the connectome in schizophrenia with diffusion spectrum imaging

Jean-Philippe Thiran, Patric Hagmann, Alessandra Griffa

Schizophrenia is a complex psychiatric disorder characterized by disabling symptoms and cognitive deficit. Recent neuroimaging findings suggest that large parts of the brain are affected by the disease, and that the capacity of functional integration betwe ...

Wiley-Blackwell2015

Connectivity and tissue microstructural alterations in right and left temporal lobe epilepsy revealed by diffusion spectrum imaging

Jean-Philippe Thiran, Alessandro Daducci, François Lazeyras, Nicolas Kunz, Alia Lemkaddem

Focal epilepsy is increasingly recognized as the result of an altered brain network, both on the structural and functional levels and the characterization of these widespread brain alterations is crucial for our understanding of the clinical manifestation ...

2014

Assessing white matter microstructure of the newborn with multi-shell diffusion MRI and biophysical compartment models

François Lazeyras, Nicolas Kunz, Hui Zhang, Kieran O'Brien

Brain white matter connections have become a focus of major interest with important maturational processes occurring in newborns. To study the complex microstructural developmental changes in-vivo, it is imperative that non-invasive neuroimaging approaches ...

Elsevier2014

Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers

Patric Hagmann, Pascal Hagmann

MRI tractography is the mapping of neural fiber pathways based on diffusion MRI of tissue diffusion anisotropy. Tractography based on diffusion tensor imaging (DTI) cannot directly image multiple fiber orientations within a single voxel. To address this li ...

Elsevier2008