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Concept

Caféine

Publications associées (7)

Ermittlung der dynamischen Eigenschaften eines mehrgeschössigen Holzrahmenbaus mittels Ausschwingversuch

Pierino Lestuzzi

Die Grundschwingzeit T1 ist einer der wichtigsten Parameter für Ingenieure bei der Ermittlung der auftretenden Erdbebenkräfte. Ist diese kleiner als die EckperiodeTC, entstehen aufgrund der dynamischen Verstärkungen grosse Kräfte auf dem Plateau des Antwor ...

2019

Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus

Rolf Gruetter, João Miguel das Neves Duarte

Diabetes affects the morphology and plasticity of the hippocampus, and leads to learning and memory deficits. Caffeine has been proposed to prevent memory impairment upon multiple chronic disorders with neurological involvement. We tested whether long-term ...

2019

Nucleus accumbens neurochemistry in human anxiety: A 7 T 1H-MRS study

Rolf Gruetter, Maria del Carmen Sandi Perez, Lijing Xin, Alina Veronika Irene Strasser

Individual differences in anxiety provide a differential predisposition to develop neuropsychiatric disorders. The neurochemical underpinnings of anxiety remain elusive, particularly in deep structures, such as the nucleus accumbens (NAc) whose involvement ...

2019

Polymorphs of Theophylline Characterized by DNP Enhanced Solid-State NMR

David Lyndon Emsley, Aaron James Rossini, Arthur César Pinon

We show how dynamic nuclear polarization (DNP) enhanced solid-state NMR spectroscopy can be used to characterize polymorphs and solvates of organic solids. We applied DNP to three polymorphs and one hydrated form of the asthma drug molecule theophylline. F ...

American Chemical Society2015

Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity

Bernard Schneider

Methamphetamine (METH) is a central nervous system psychostimulant with a high potential for abuse. At high doses, METH causes a selective degeneration of dopaminergic terminals in the striatum, sparing other striatal terminals and cell bodies. We previous ...

Elsevier2013

Concise Synthesis of Complicated Polypropionates through One-Pot Dissymmetrical Two-Directional Chain Elongation

Pierre Vogel, Maris Turks, Claudia Jana Exner, Freddy Fonquerne

Herein, a major breakthrough in a sulfur dioxide-mediated oxyallylation cascade reaction is reported that allows the preparation of complex long-chain polyketide fragments with more than ten stereogenic centers through a carefully designed desymmetrization ...

2011

Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats

Rolf Gruetter, João Miguel das Neves Duarte

Type 1 diabetes can affect hippocampal function triggering cognitive impairment through unknown mechanisms. Caffeine consumption prevents hippocampal degeneration and memory dysfunction upon different insults and is also known to affect peripheral glucose ...

Wiley-Blackwell2009