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Concept

Placentalia

Publications associées (5)

Species-specific regulation of XIST by the JPX/FTX orthologs

Olga Marie Louise Rosspopoff

X chromosome inactivation (XCI) is an essential process, yet it initiates with remarkable diversity in various mammalian species. XIST, the main trigger of XCI, is controlled in the mouse by an interplay of lncRNA genes (LRGs), some of which evolved concom ...

OXFORD UNIV PRESS2023

DUX-family transcription factors regulate zygotic genome activation in placental mammals

Didier Trono, Evaristo Jose Planet Letschert, Julien Léonard Duc, Sonia Verp, Andrea Coluccio, Alberto De Iaco

In animal embryos, transcription is mostly silent for several cell divisions, until the release of the first major wave of embryonic transcripts through so-called zygotic genome activation (ZGA). Maternally provided ZGA-triggering factors have been identif ...

2017

Kinematic and gait similarities between crawling human infants and other quadruped mammals

Auke Ijspeert, Ludovic Righetti

Crawling on hands and knees is an early pattern of human infant locomotion, which offers an interesting way of studying quadrupedalism in one of its simplest form. We investigate how crawling human infants compare to other quadruped mammals, especially pri ...

Frontiers Media Sa2015

The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation

Friedrich Beermann, Simona Frateschi

The serine protease CAP1/Prss8 is crucial for skin barrier function, lung alveolar fluid clearance and has been unveiled as diagnostic marker for specific cancer types. Here, we show that a constitutive knockout of CAP1/Prss8 leads to embryonic lethality. ...

Public Library of Science2013

NEOBASE: databasing the neocortical microcircuit

Henry Markram

Mammals adapt to a rapidly changing world because of the sophisticated perceptual and cognitive function enabled by the neocortex. The neocortex, which has expanded to constitute nearly 80% of the human brain seems to have arisen from repeated duplication ...

2005