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Concept

Dedifferentiation

Publications associées (4)

Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle

Noaf Salah Ali Alwahab

Skeletal muscle holds significant regenerative potential but is incapable of restoring tissue loss caused by severe injury, congenital defects or tumour ablation. Consequently, skeletal muscle models are being developed to study human pathophysiology and r ...

WILEY2018

The chromatin remodeller Chd7 and the calcium ATPase Serca2 - adding new facets to the role of Notch in Hematopoiesis and T-ALL

Monique Coersmeyer

Project I: Chd7 Deficiency does not affect N1-driven T-ALL Induction and Maintenance nor impair Hematopoiesis Notch1 has been shown to be a key driver in pediatric T-cell acute lymphobastic leukemia (T-ALL). Previous work in the lab identified the chromati ...

EPFL2015

Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells

Yann Barrandon, Stéphanie Claudinot, Paola Bonfanti, Alessandro Wataru Amici

The thymus develops from the third pharyngeal pouch of the anterior gut and provides the necessary environment for thymopoiesis (the process by which thymocytes differentiate into mature T lymphocytes) and the establishment and maintenance of self-toleranc ...

2010

MOVE Processors That Self-replicate and Differentiate

Pierre-André Mudry, Yann Thoma, Joël Rossier

This article describes an implementation of a basic multiprocessor system that exhibits replication and differentiation abilities on the POEtic tissue, a programmable hardware designed for bio-inspired applications. As for a living organism, whose existenc ...

2006