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Concept

Cholestérol

Publications associées (26)

Frequent walkers: from healthy individual behaviours to sustainable mobility futures

Derek Pierre Christie

Walking is often taken for granted or considered as an ancillary activity. Little is known about the distribution of walking in contemporary populations, and even less about the few people who walk for an hour or more in public space on most days of the we ...

EPFL2018

Associations between Daily Walking and Subclinical Health Markers in a Swiss City

Vincent Kaufmann, Emmanuel Pierre Jean Ravalet, Idris Guessous, Derek Pierre Christie

Every year, the Health Bus (Bus Santé) enables a representative sample of around 1000 members of the non-institutionalised adult population of Geneva, Switzerland, to undergo a health evaluation including physical measurements, blood tests and questionnair ...

2017

Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene

Vincenzo Sorrentino

Cellular cholesterol metabolism is subject to tight regulation to maintain adequate levels of this central lipid molecule. Herein, the sterol-responsive Liver X Receptors (LXRs) play an important role owing to their ability to reduce cellular cholesterol l ...

2017

Sexual dimorphism in hepatic lipids is associated with the evolution of metabolic status in mice

Rolf Gruetter, Ana Francisca Leal Silva Soares, Hongxia Lei, Marc Moniatte, Jonathan Paz Montoya

Ectopic lipid accumulation in the liver is implicated in metabolic disease in an age- and sex-dependent manner. The role of hepatic lipids has been well established within the scope of metabolic insults in mice, but has been insufficiently characterized un ...

Wiley-Blackwell2017

Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2

Johan Auwerx

Sirtuin 3 (Sirt3) is an NAD(+)-dependent mitochondrial deacetylase associated with superoxide dismutase 2 (SOD2)-mediated protection from oxidative stress. We have reported accelerated weight gain and impaired metabolic flexibility in atherosclerotic Sirt3 ...

Springer2016

Treatment with the GPR55 antagonist CID16020046 increases neutrophil activation in mouse atherogenesis

Nikolaos Stergiopoulos

Endocannabinoids modulate atherogenesis by triggering different receptors. Recently, orphan G protein-coupled receptors (GPRs) were suggested to be activated by endocannabinoids, possibly regulating vasorelaxation. Here, we investigated whether GPR55 antag ...

Schattauer Gmbh-Verlag Medizin Naturwissenschaften2016