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Publications associées (28)

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Synthesis and application of bifunctional hypervalent iodine reagents for peptide modification

Elija Grinhagena

Protein-protein interactions (PPIs) are responsible for regulating many biological processes in human bodies. PPIs often have a large binding site and often interact through an alpha helical segment. Therefore, the inhibition of PPIs can be difficult using ...

EPFL2023

Triple Crossed Flexure Pivot Based on a Zero Parasitic Center Shift Kinematic Design

Simon Nessim Henein, Etienne Frédéric Gabriel Thalmann

Thanks to their absence of play, absence of contact friction and possible monolithic fabrication, flexure pivots offer advantages over traditional bearings in small-scale, high accuracy applications and environments where lubrication and wear debris are pr ...

2022

Experimental Investigation of Enhanced Grooves for Herringbone Grooved Journal Bearings

Jürg Alexander Schiffmann, Patrick Hubert Wagner, Philipp Kaspar Bättig

This paper presents the results of a theoretical and experimental investigation of the potential of enhanced groove geometries to increase the bearing clearance of a Herringbone Grooved Journal Bearing (HGJB) supported rotor. The theoretical study investig ...

2022

Reinforcing hydrogels with in situ formed amorphous CaCO3

Esther Amstad, Matteo Hirsch, Huachuan Du, Ran Zhao, Michael David Kessler, Tianyu Yuan

Hydrogels are often employed for tissue engineering and moistening applications. However, they are rarely used for load-bearing purposes because of their limited stiffness and the stiffness-toughness compromise inherent to them. By contrast, nature uses hy ...

ROYAL SOC CHEMISTRY2022

Mechanical reinforcement of granular hydrogels

Esther Amstad, Alvaro Lino Boris Charlet, Francesca Bono

Granular hydrogels are composed of hydrogel-based microparticles, so-called microgels, that are densely packed to form an ink that can be 3D printed, injected or cast into macroscopic structures. They are frequently used as tissue engineering scaffolds bec ...

ROYAL SOC CHEMISTRY2022

Numerical and experimental investigation of spiral-grooved gas journal bearings

Elia Iseli

Small-scale turbomachinery is increasingly used in carbon-free energy conversion systems, such as commercial or domestic scale heat pumps, fuels cells for transportation and waste heat recovery. The usage of aerodynamic bearings allows the design of compac ...

EPFL2022

Re:Crete – reuse of concrete elements in new structures: A footbridge prototype

Corentin Jean Dominique Fivet, Maléna Bastien Masse, Jan Friedrich Georg Brütting, Célia Marine Küpfer, Julie Rachel Devènes

Concrete accounts for the largest share of worldwide building material use and waste generation, with cement production being responsible for approximately 9% of global anthropogenic CO2 emissions. A currently untapped strategy to significantly reduce thes ...

CRC Press2022

Deformation and Fracture of Tough Microstructured Hydrogels

Michael David Kessler

Many natural materials are structured on different length scales. This structuring often leads to an intricate interplay between soft and stiff components, which significantly improves the fracture toughness of these materials. A class of soft material tha ...

EPFL2022